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research Insulin Resistance, Acanthosis Nigricans, and Polycystic Ovaries Associated with a Circulating Inhibitor of Postbinding Insulin Action

24 citations , May 1985 in “The Journal of Clinical Endocrinology & Metabolism”

In this case study, the authors identified a circulating low molecular weight inhibitor that may contribute to insulin resistance in a woman with acanthosis nigricans and polycystic ovary syndrome.

research Accelerative action of topical piperonylic acid on mice full thickness wound by modulating inflammation and collagen deposition

3 citations , October 2021 in “PLoS ONE”

In this study, topical piperonylic acid was found to improve wound healing in mice by activating EGFR and modulating gene expression related to the healing process.

research Action Mechanism of Chamaecyparis obtusa Oil on Hair Growth

9 citations , December 2013 in “Toxicological Research”

This study found that Chamaecyparis obtusa oil increased hair follicle cell proliferation and maintained the anagen phase in mice, suggesting a potential for promoting hair growth.

research Modulation of glucocorticoid action and the treatment of type-2 diabetes

54 citations , December 2007 in “Best Practice & Research Clinical Endocrinology & Metabolism”

This review discusses the potential of targeting glucocorticoid action as a treatment strategy for obesity and type-2 diabetes, highlighting promising animal study results but reports no new clinical findings.

research Hair growth promoting effect and action mechanism of Chrysanthemum zawadskii extract

January 2014

This study found that Chrysanthemum zawadskii extract may promote hair growth by inducing an earlier conversion of telogen to anagen and increasing the proliferation of dermal papilla cells in mice and human hair follicle cultures.

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Community Join

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community Claim: Insulin resistance increases the enzyme that creates DHT and affects the liver's ability to control hormones

in Research/Science 4 upvotes 11 months ago

Insulin resistance may increase DHT production, contributing to hair loss, and addressing it through diet, nutrients, and natural DHT blockers like saw palmetto and pumpkin seed oil could help reverse hair loss. Some users prefer medications like finasteride for more effective results.

community Interesting new publication suggesting that MPB should be assessed as a early warning sign for type-2 diabetes.

15 upvotes 8 years ago

Male pattern baldness (MPB) may be an early warning sign for type 2 diabetes due to its association with insulin resistance. Treatments discussed include testosterone therapy and finasteride, which affects hormone levels related to hair loss and insulin sensitivity.

community Serum based on plant extracts boosts hair growth in weeks.

44 upvotes 11 months ago

A serum containing Centella asiatica extracellular vesicles, IGF-1, FGF-7, and caffeine significantly improved hair thickness, density, length, and reduced hair loss after 56 days. The conversation also discusses how treatments like finasteride, minoxidil, and ketoconazole address different aspects of hair loss by reducing DHT, improving blood flow, and lowering inflammation.

community 166 days of scalp massage,. Update i dont know what to think….

in Chat 20 upvotes 6 months ago

Scalp massages may show slight improvement in hair appearance, but users suggest more aggressive treatments like finasteride or minoxidil for better results. Some users believe lighting and angles affect photo comparisons, and recommend combining massages with medication.

community On the big 6 but very slow , needs acceleration

in Is this regrowth? 30 upvotes 1 year ago

The user is using a hair regrowth protocol including dutasteride, topical and oral minoxidil, dermarolling, ketoconazole shampoo, and tretinoin, but is experiencing slow progress and seeks advice for faster regrowth. Suggestions include quitting smoking, adjusting the regimen, and considering additional treatments like topical finasteride or RU58841.

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Learn

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learn Metformin

diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

Can metformin improve scalp health in people with insulin resistance or PCOS? There is no controlled trial showing that metformin improves scalp hair. The PCOS studies most often cited measured unwanted body hair, not scalp density, and a published case report describes hair loss during metformin treatment; any use for hair would be off-label and a decision for a prescribing doctor.

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

learn Vascular Endothelial Growth Factor

learn sh-Polypeptide-7

learn Epidermal Growth Factor

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