research Microneedle-Based Approaches for Skin Disease Treatment
This review summarizes the application of microneedles in treating various skin diseases and highlights challenges like low drug loading, noting no new clinical results are reported.
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research Characterisation of Myotonic Dystrophy type I cell models and drug evaluation by a cell- based quantification platform.
Antisense oligonucleotides show promise for treating Myotonic Dystrophy type I.
research Product development and comparison of physio- chemical parameters of traditional drug recipe mentioned in Thalpathe pillium for hair growth
This study concluded that freeze-dried and natural forms of a hair growth promoter derived from traditional recipes have mostly similar chemical constituents.
research A Semi-Dissolving Microneedle Patch Incorporating TEMPO-Oxidized Bacterial Cellulose Nanofibers for Enhanced Transdermal Delivery
The researchers developed semi-dissolving microneedle patches using TEMPO-oxidized bacterial cellulose nanofibers, which allow effective transdermal drug delivery by forming micro-channels for large drug quantities, overcoming traditional microneedles' low drug loading.
research The effects of particle properties on nanoparticle drug retention and release in dynamic minoxidil foams
This study found that polymeric nanoparticles retained more minoxidil and facilitated superior drug permeation compared to lipid nanoparticles, although premature drug release affected formulation performance.
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5 / 14 resultscommunity Homemade Topical Finasteride Formula?
User wants to make homemade topical finasteride to minimize side effects and asks about using glycerin, stirring time, storage, and alternative solvents. Another user's comment is unclear.
community The Big Fat Layer / Remedies: Cetirizine
Treating hair loss with various remedies, such as Cetirizine and the Big3 complex (minoxidil, finasteride, and RU58841), which have properties like adipogenic, anti-fibrotic and anti-inflammatory. References to research studies are also included.
community Does melatonin dissolve in isopropyl alcohol
The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.
community Out of curiosity, why are Finasteride pills formulated as small tablets, while Dutasteride pills are much larger soft gel capsules?
Finasteride and Dutasteride are used for hair loss, with Dutasteride often in gel form for better bioavailability. Switching from Finasteride to Dutasteride is common, with some users combining treatments like Minoxidil for improved results.
community PSA: Not all Finasteride generics are created equal, effectiveness and severity of side-effects can vary by manufacturer.
Switching generic finasteride manufacturers can reduce side effects while maintaining effectiveness. Different fillers in generics may affect bioavailability and cause varying side effects.
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