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Abdominal Fat Quantity and Distribution in Women with Polycystic Ovary Syndrome and Its Relation to Insulin Resistance

research Abdominal Fat Quantity and Distribution in Women with Polycystic Ovary Syndrome and Extent of Its Relation to Insulin Resistance

270 citations , April 2007 in “The Journal of Clinical Endocrinology and Metabolism”

This study found that PCOS patients had higher amounts of central abdominal fat compared to weight-matched controls, which was associated with increased insulin resistance.

research Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth

222 citations , January 2014 in “International journal of reproductive medicine”

This paper reviews the complex pathophysiology of polycystic ovary syndrome, exploring how hormonal and metabolic disturbances contribute to its symptoms and related health risks, but it presents no new findings.

research Insulin administration alters gonadal steroid metabolism independent of changes in gonadotropin secretion in insulin-resistant women with the polycystic ovary syndrome.

202 citations , January 1989 in “Journal of Clinical Investigation”

This study indicates that insulin changes sex hormone levels in insulin-resistant women with polycystic ovary syndrome without affecting gonadotropin release, challenging the idea that hyperinsulinemia directly causes hyperandrogenism in PCO.

research Role of insulin, insulin‐like growth factor‐1, hyperglycaemic food and milk consumption in the pathogenesis of acne vulgaris

200 citations , August 2009 in “Experimental dermatology”

This article reviews the role of IGF-1 in acne pathogenesis and discusses how diet and smoking may influence insulin/IGF-1 signaling, but reports no new clinical results.

research The Human Sebocyte Culture Model Provides New Insights into Development and Management of Seborrhoea and Acne

198 citations , January 1998 in “Dermatology”

This review discusses human sebocyte in vitro models for studying sebaceous gland function and control but reports no new clinical results, highlighting hormonal effects and the impact of retinoids on sebocyte activity.

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Community Join

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community Insane shed 3 months on Fin + Min Oral

88 upvotes 3 months ago

The user experienced severe hair shedding after starting oral Minoxidil and Finasteride, possibly due to stress from a breakup. Many suggest the shedding resembles alopecia areata and recommend seeing a doctor immediately.

community Insane hairline regrowth with natural supps and minox

in Update 103 upvotes 6 months ago

A 23-year-old achieved significant hairline regrowth using minoxidil, saw palmetto, collagen peptides, biotin, omega-3, iron, ketoconazole shampoo, and scalp care techniques, without finasteride or dutasteride. The user attributes success to this combination but is unsure which element is most effective.

community Insane shedding after upping minoxidil dose.

1 upvotes 11 months ago

The user experienced increased hair loss after increasing their minoxidil dose to 5mg and is considering switching to dutasteride while on testosterone replacement therapy. They are also using finasteride, microneedling, and considering adding Nizoral and caffeine serum to their regimen.

community Claim: Insulin resistance increases the enzyme that creates DHT and affects the liver's ability to control hormones

in Research/Science 4 upvotes 11 months ago

Insulin resistance may increase DHT production, contributing to hair loss, and addressing it through diet, nutrients, and natural DHT blockers like saw palmetto and pumpkin seed oil could help reverse hair loss. Some users prefer medications like finasteride for more effective results.

community Insane regression after hyper-responding (17M) AMA

in Progress Pictures 137 upvotes 1 year ago

A 17-year-old experienced significant hair loss after switching from topical to oral minoxidil and adding finasteride. The recommendation is to return to topical minoxidil and continue with finasteride or consider dutasteride.

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Learn

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learn Scalp Micropigmentation

Does insurance cover scalp micropigmentation? Insurance typically does not cover scalp micropigmentation as it is considered cosmetic.

learn Hair Transplant

Does insurance cover hair transplants? Insurance usually doesn't cover hair transplants unless for specific medical conditions.
What are the aftercare instructions following the hair transplant procedure? Follow your provider's aftercare instructions to ensure optimal healing and results.

learn Metformin

diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

Can metformin improve scalp health in people with insulin resistance or PCOS? There is no controlled trial showing that metformin improves scalp hair. The PCOS studies most often cited measured unwanted body hair, not scalp density, and a published case report describes hair loss during metformin treatment; any use for hair would be off-label and a decision for a prescribing doctor.

learn L-cysteine

Can taking L-cysteine orally really strengthen hair from the inside? L-cysteine may help strengthen hair if there's a deficiency, but results vary.

learn Low Level Laser Therapy

laser therapy for anti-inflammatory and likely insignificant hair regrowth effects

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Clinics

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