This study suggests that supporting cells are the origin of regenerated haircells in the avian basilar papilla, with epidermal growth factor as a potential trigger, and indicates a possibility of haircell regeneration in mammalian vestibular epithelia.
This study identified changes in transcription factor gene expression across various signaling pathways during innerearhaircell regeneration in birds, revealing patterns and potential new pathways for future investigation.
This review covers recent developments in innerear therapeutics and gene delivery methods but reports no new clinical results; it highlights potential strategies for treating hearing and balance disorders.
April 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”
This study successfully isolated innerear-specific exosomes from perilymph samples of sensorineural hearing loss patients using a novel immunomagnetic approach, enabling groundbreaking liquid biopsy diagnostics.