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protein that inhibits cell cycle progression to prevent uncontrolled division

p15INK4b, also known as CDKN2B, is a protein that helps regulate the cell cycle by inhibiting certain enzymes called cyclin-dependent kinases (CDKs). This inhibition prevents cells from dividing uncontrollably, which is crucial for preventing cancer. In the context of hair and alopecia, disruptions in the regulation of cell division can affect hair follicle function and growth.

Related Terms

• Cyclin-dependent kinase inhibitor
• Cell cycle regulation
• Tumor suppressor gene
• p16