Search

for
Search:

Research

5 / 1000+ results

research The Mechanisms of Anabolic Steroids, Selective Androgen Receptor Modulators and Myostatin Inhibitors

2 citations , June 2022 in “대한스포츠의학회지”

This article reviews the development of selective androgen receptor modulators and myostatin inhibitors as performance-enhancing drugs, highlighting ongoing challenges in achieving truly tissue-selective anabolic agents and reporting no new experimental findings.

research Theoretical investigation on the construction of hair follicle membranes and the transdermal drug delivery mechanisms of JAK inhibitors via distinct pathways

February 2026 in “Colloids and Surfaces A Physicochemical and Engineering Aspects”

Using molecular dynamics simulations, this study explored the uptake processes of JAK inhibitors on stratum corneum and hair follicle membranes, revealing a unique interaction mechanism in the hair follicle and offering insights into transdermal drug delivery pathways.

Role of DNA Methylation in the Pathogenesis of Skin Disorders: Mechanisms, Inhibitors of Methylation-Related Enzyme, and Molecular Docking Studies

research Role of DNA Methylation in the Pathogenesis of Skin Disorders: Mechanisms, Inhibitors of Methylation‐Related Enzyme, and Molecular Docking Studies

January 2025 in “BioMed Research International”

This study highlights the role of abnormal DNA methylation in skin disorders such as atopic dermatitis and psoriasis, suggesting these epigenetic changes may serve as biomarkers and targets for potential treatments.

research Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts

57 citations , April 2009 in “The Journal of Steroid Biochemistry and Molecular Biology”

This study found that despite the presence of steroidogenesis inhibitors, CRPC tumor cells adapt to continue synthesizing androgens, suggesting a need for more effective androgen axis targeting.

research Mechanistic Underlying Anti-diabetic Potential of Eclipta alba Flavonoids against Aldose Reductase Inhibitory Action

1 citations , February 2025 in “South Asian Research Journal of Pharmaceutical Sciences”

This study used in-silico molecular docking to evaluate the antidiabetic potential of Eclipta alba leaf flavonoids, finding that compounds like apigenin, syringic acid, and vanillic acid effectively bind to the target protein aldose reductase, suggesting a promising inhibitory action.

View more "inhibitory mechanism" in research →

Community Join

5 / 1000+ results

community Mechanism of action of alfatradiol (17 alpha estradiol)

5 upvotes 2 years ago

The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

community The mechanism of androgenic alopecia

36 upvotes 11 months ago

DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

community Does anyone know about the mechanism between creatine and 5-alpha reductase?

7 upvotes 7 years ago

Creatine may raise DHT levels, potentially affecting hair loss, but its exact mechanism is unclear. Some users report that finasteride remains effective even when taking creatine.

community Minoxidil is a 5ar inhibitor according to research

150 upvotes 11 months ago

Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

community When will FAK Inhibitors / Standford Hydrogel be on the market for hair transplants?

9 upvotes 8 months ago

The conversation discusses the delay in bringing FAK inhibitors and Stanford's hydrogel to market for hair transplants, with a preference for FAK inhibitors over Verteporfin due to their superior potential in preventing scarring. The user expresses frustration over the slow progress and hopes for faster development by companies like FAKnostics.

View more "inhibitory mechanism" in community →

Learn

5 / 801 results

learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

learn PP405

mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

learn Saw Palmetto

a natural and far less effective alternative to Finasteride

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

View more "inhibitory mechanism" in learn →

Experts

— no results

Try a deeper search in experts →

Clinics

— no results

Try a deeper search in clinics →