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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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5 / 13 resultslearn Epidermal Growth Factor
learn Baricitinib
JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases
learn Tofacitinib
a JAK inhibitor for alopecia areata and other autoimmune conditions
learn PP405
mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
Research
5 / 1000+ results
research Identification of Relay Cells and Interneurons in the Cuneate Nucleus
The cuneate nucleus has two main neuron types: relay neurons and interneurons.
research Relationships Between Hair-Follicle Afferent Axons and Glycine-Immunoreactive Profiles in Cat Spinal Dorsal Horn
Aδ-LTMRs have complex synapses with glycine, while Aβ-LTMRs have simpler ones.
research Neurosteroids Involved in Regulating Inhibition in the Inferior Colliculus
Neurosteroids help balance brain signals when certain inhibitions are reduced.
research Adaptive Balance in the Posterior Cerebellum
The posterior cerebellum helps maintain balance by adapting to sensory inputs and self-motion.
research Production of 5α-Reduced Neurosteroids Is Developmentally Regulated and Shapes GABA A Miniature IPSCs in Lamina II of the Spinal Cord
Neurosteroids regulate synaptic inhibition in the spinal cord and may help manage spinal pain.
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5 / 1000+ resultscommunity Rosemary oil's potency as a dht blocker
Rosemary extract showed high inhibitory activity against DHT, similar to finasteride and dutasteride, but the conversation includes skepticism about its effectiveness in humans since the study was done on mice and rosemary oil is often considered ineffective based on personal experiences. Some suggest trying rosemary oil alongside other treatments, while others emphasize the difference between the extract used in the study and the oil.
community Better Than Minoxidil? Topical Sodium Valproate
Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.
community Bile Acid-Mediated DHT Dysregulation Hypothesis
Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.
community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia
IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.
community Head and Shoulders 2-in-1 shampoo and conditioner use resulting in hair growth by reducing scalp inflammation and DHT?
User experienced new hair growth after using Head and Shoulders 2-in-1 shampoo/conditioner, attributing it to pyrithione zinc reducing scalp inflammation and DHT. They seek others' experiences with anti-dandruff products.