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research Controversial Concepts in the Classification of Infundibular Squamous Cell Carcinoma and Tricholemmal Carcinoma

5 citations, May 2013 in “The American Journal of Dermatopathology”

The author now believes tricholemmal carcinoma is a rare type of infundibular squamous cell carcinoma and more research is needed on these tumors.

Pigmented Epithelioid Melanocytoma (PEM)/Animal Type Melanoma (ATM): Quest for an Origin. Report of One Unusual Case Indicating Follicular Origin and Another Arising in an Intradermal Nevus

research Pigmented Epithelioid Melanocytoma (PEM)/Animal Type Melanoma (ATM): Quest for an Origin. Report of One Unusual Case Indicating Follicular Origin and Another Arising in an Intradermal Nevus

4 citations, August 2017 in “International journal of molecular sciences”

The conclusion is that Pigmented Epithelioid Melanocytoma can start from hair follicle stem cells or from a mole on the skin.

research Stem Cell Quiescence Acts as a Tumor Suppressor in Squamous Tumors

66 citations, December 2013 in “Nature Cell Biology”

Inactive hair follicle stem cells help prevent skin cancer.

research Mechanical Forces in Skin Disorders

65 citations, March 2018 in “Journal of Dermatological Science”

Skin problems can be caused or worsened by physical forces and pressure on the skin.

research Sox9 Expression in Canine Epithelial Skin Tumors

8 citations, July 2015 in “European journal of histochemistry”

Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.

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community I think I’ve finally found the reason for my hair loss

in Chat 98 upvotes 2 months ago

The user experienced hair loss since 2019 and tried finasteride, dutasteride, RU58841, and ketoconazole shampoo without success. A scalp biopsy showed scarring and inflammation from folliculitis, indicating chronic inflammation was affecting treatment effectiveness.

community Fibrosing alopecia in a pattern distribution

in Research/Science 14 upvotes 11 months ago

A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 2 years ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 6 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.