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Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity

research Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity

August 2023 in “International Journal of Molecular Sciences”

This study observed unexpected heterogeneity among pigment cells in human scalp hair follicles, identifying immature melanocyte populations outside traditional pigment production zones, raising questions about their potential roles beyond melanin synthesis.

research Immunological and Metabolic Causes of Infertility in Polycystic Ovary Syndrome

3 citations , May 2023 in “Biomedicines”

This article reviews the immunometabolic mechanisms linking polycystic ovary syndrome to infertility and stresses the need for interdisciplinary approaches to treat PCOS-related fertility issues; it reports no new clinical results.

research Hypochlorous Acid: Clinical Insights and Experience in Dermatology, Surgery, Dentistry, Ophthalmology, Rhinology, and Other Specialties

November 2025 in “Biomedicines”

This review highlights hypochlorous acid's potential benefits in various medical fields due to its antimicrobial and healing properties but stresses the need for further research on dosing and product development.

Chronic Inflammatory Diseases Stimulated by Current Lifestyle: How Diet, Stress Levels, and Medication Prevent Our Body from Recovering

research Chronic inflammatory diseases are stimulated by current lifestyle: how diet, stress levels and medication prevent our body from recovering

119 citations , January 2012 in “Nutrition & Metabolism”

This article suggests that modern lifestyle changes, including diet, stress, and chronic anti-inflammatory medication use, may disrupt the natural process of inflammation resolution, increasing vulnerability to chronic disease.

research Symptom management in inflammatory bowel disease

8 citations , April 2015 in “Expert Review of Gastroenterology & Hepatology”

This review highlights the importance of promptly addressing symptoms in patients with inflammatory bowel disease, whether they stem from disease activity, medication side effects, or related autoimmune conditions, but it reports no new findings.

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Community Join

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community OND-1 "Cyclosporine A” New hair loss treatment

in Research/Science 28 upvotes 5 months ago

Orient Bio is developing a PLGA formulated version of Cyclosporine A to stimulate hair growth without its immunosuppressant effects. Users discuss various treatments like Clascoterone, PP405, minoxidil, and tacrolimus, expressing hope for new developments and sharing personal experiences with these treatments.

community My Theory Of Androgenic Alopecia

16 upvotes 9 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community I Recovered From Severe Hair Loss: My 8-Month Regrowth Recovery — Full Timeline, Photos & Treatment Data

35 upvotes 4 months ago

A 29-year-old male experienced significant hair regrowth over 8 months using a protocol of oral Minoxidil, Dutasteride, Pyrithione Zinc Shampoo, and peptides GHK-CU, BPC-157, and TB-500. The treatment led to improved scalp coverage, reduced hair loss, and thicker hair, although results may vary for others.

community Are carbohydrates needed for hair growth

26 upvotes 2 years ago

A 47-year-old male experienced significant hair loss after losing 37 kg in 6 months on a low-carb diet and started taking biotin, zinc, iron, selenium, and spectral dcn-n. Replies suggest that while carbs are not directly needed for hair growth, they help regulate hormones and nutrient absorption, and rapid weight loss can also contribute to hair loss.

community Finasteride does deplete important nuero-active steroids

11 upvotes 3 years ago

Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

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Learn

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learn Thymosin Beta 4

learn capsicum

Is capsicum safe for sensitive scalps or inflammatory hair loss? Capsicum may irritate sensitive scalps and worsen inflammatory hair loss.

learn Cetirizine

What makes cetirizine a unique anti-inflammatory option for your scalp? Laboratory work reports that cetirizine lowers PGD2 and other inflammatory mediators, which is why researchers have proposed it for the scalp. There is no approved topical product and the clinical evidence is one small unblinded pilot study in pattern hair loss, so scalp use is off-label and experimental.

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