This review discusses the role of androgen metabolism and perifollicular inflammation in the progression of androgenetic alopecia and reports no new clinical results.
This commentary discusses informal observations of poor or worsening outcomes in some patients after hair transplant surgery for androgenetic alopecia, suggesting the need for further research.
2 citations
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November 2014 in “The journal of investigative dermatology/Journal of investigative dermatology”
This case report observed that oral tofacitinib treatment resolved both alopecia universalis and plaque psoriasis in a patient, possibly by targeting shared inflammatory pathways.
October 2022 in “International Research Journal of Modernization in Engineering Technology and Science”
This review discusses the development and rapid approval of COVID-19 vaccines and notes the observation of autoimmune disorders, such as alopecia areata, following vaccination; it provides no new clinical results.
Hot weather can increase hair shedding, possibly due to dehydration and active sebaceous glands. Using shampoos with salicylic acid or zinc pyrithione may help; daily anti-inflammatory use is not recommended.
Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.
Hair loss treatments like finasteride, dutasteride, minoxidil, and RU58841. Users discuss "DHT itch" at receding hairlines and suggest using dutasteride or ketoconazole shampoo for relief.
Microneedling the scalp can cause sneezing, runny nose, and watery eyes due to nerve stimulation, histamine release, reflex actions, or sinus relief. Several users experience similar symptoms.
Scalp tension from the occipitalis muscle is theorized to contribute to hair loss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.
What makes cetirizine a unique anti-inflammatory option for your scalp?Laboratory work reports that cetirizine lowers PGD2 and other inflammatory mediators, which is why researchers have proposed it for the scalp. There is no approved topical product and the clinical evidence is one small unblinded pilot study in pattern hair loss, so scalp use is off-label and experimental.