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      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

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      community Hopefully a logical question regarding dermarolling.

      in Microneedling 5 years ago
      A user discusses using dermastamping for hair loss and questions the timing of applying a mixture of peppermint oil, spearmint oil, rosemary oil, and castor oil due to their anti-inflammatory effects. They wonder if waiting 10 hours after stamping would be more effective.

      community Hair Loss “Cure” for Inflammation: Topical Roflumilast

      in Research/Science  32 upvotes 3 weeks ago
      Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

      community The 'DHT itch' is real - notes from a casual bodybuilder

      in Chat  115 upvotes 1 year ago
      The "DHT itch" is real and likely due to inflammation at the hair follicle, exacerbated by increased testosterone or androgens. Treatments mentioned include dutasteride, minoxidil, finasteride, and various topical solutions.

      community Trialing the probiotics BB536, PTA 6475 so you don’t have to

      in Research/Science  75 upvotes 7 months ago
      Probiotics like L. reuteri ATCC PTA 6475 and B. longum BB536 may improve hair growth and density by reducing inflammation and reversing DHT damage. The user is trialing these probiotics personally, ordering them from the U.S. to Canada, and plans to continue if no adverse effects occur.

      community Regrowth with only Nizoral and Lifestyle Changes; focusing on scalp health & nervous system

      in Is this regrowth?  85 upvotes 2 weeks ago
      The user reported subtle hair regrowth by focusing on scalp health and lifestyle changes, using Nizoral shampoo and methods to reduce inflammation and cortisol, without using finasteride, minoxidil, or other common treatments. Opinions in the conversation varied, with some skeptical of the results and others acknowledging the potential benefits of addressing scalp health and inflammation.