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GlossaryIndomethacin

nonsteroidal anti-inflammatory drug used to reduce inflammation and pain

Indomethacin, also known by the brand name Indocin, is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce inflammation, pain, and fever. It works by inhibiting the production of prostaglandins, which are chemicals in the body that cause inflammation and pain. Indomethacin is commonly prescribed for conditions like arthritis, gout, and bursitis.

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Diphlorethohydroxycarmalol, Isolated from Ishige Okamurae, Increases Prostaglandin E2 through the Expression of Cyclooxygenase-1 and -2 in HaCaT Human Keratinocytes

research Diphlorethohydroxycarmalol, Isolated from Ishige Okamurae, Increases Prostaglandin E2 through the Expression of Cyclooxygenase-1 and -2 in HaCaT Human Keratinocytes

9 citations , November 2012 in “Biomolecules & therapeutics”

A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.

research Salt-Losing Tubulopathy and Chronic Dermatitis

July 2018 in “Kidney international”

Genetic testing for EGFR mutations is crucial in similar cases.

research Skin Permeability and Transdermal Delivery Route of 50-nm Indomethacin-Loaded PLGA Nanoparticles

39 citations , August 2017 in “Colloids and Surfaces B: Biointerfaces”

50-nm nanoparticles are better at penetrating skin and targeting hair follicles for drug delivery than 100-nm ones.

research Aromatase Inhibition by Letrozole Attenuates Kainic Acid-Induced Seizures but Not Neurotoxicity in Mice

11 citations , April 2018 in “Epilepsy research”

Letrozole reduces seizures but not brain damage in mice.

research A Case of Idiopathic Follicular Mucinosis Treated Successfully with Cyclosporine

December 2024 in “PubMed”

Cyclosporine effectively treated a woman's stubborn skin condition.

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community 1% cetirizine (available in allergy medicines) for androgenetic alopecia

50 upvotes 6 years ago

The conversation discusses using 1% cetirizine, an antihistamine, as a potential treatment for androgenetic alopecia (hair loss). One user plans to try cetirizine instead of finasteride, while others are curious or skeptical about its effectiveness, discussing the role of inflammation in hair loss.

community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 1 year ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.