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research Loss of keratin 10 is accompanied by increased sebocyte proliferation and differentiation

36 citations , January 2004 in “European journal of cell biology”

This study found that in mice, deleting the keratin 10 gene enhances sebocyte differentiation and increases secretion of sebum and certain lipids without affecting proliferation-associated keratins.

research 115 EXOGENOUS TESTOSTERONE ALONE OR WITH FINASTERIDE INCREASES PHYSICAL PERFORMANCE, GRIP STRENGTH, AND LEAN BODY MASS IN OLDER MEN WITH LOW SERUM TESTOSTERONE

January 2005 in “Journal of Investigative Medicine”

This study found that testosterone therapy improved physical performance, strength, lean body mass, and serum cholesterol in older men with low testosterone levels, with or without the addition of finasteride.

5α-Reductase Inhibitors: A New Hope in Dermatology?

research 5alpha-reductase inhibitors - a new hope in dermatology?

15 citations , March 1997 in “International Journal of Dermatology”

This article discusses the potential use of 5α-reductase inhibitors in dermatology and reports no new clinical results; the authors suggest further exploration of their dermatological applications.

research RETRACTED: Serum lipids may causally affect the occurrence of alopecia areata: A Mendelian randomization study

3 citations , June 2024 in “Skin Research and Technology”

Higher LDL lipids may increase alopecia areata risk, while higher triglycerides may decrease it.

research 1302 Disturbed sebum and microbiome composition in sensitive scalp

April 2018 in “Journal of Investigative Dermatology”

This study found that sensitive scalp is characterized by increased pH levels, redness, altered sebum composition, and a disrupted microbiome, suggesting these features could inform treatment approaches.

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Community Join

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community Dutasteride absolutely nukes hair DHT

in Finasteride/Dutasteride 486 upvotes 1 year ago

Dutasteride significantly reduces DHT levels, potentially more effectively than finasteride, and is used to treat hair loss. Some users report side effects like reduced libido and mood changes, while others experience hair regrowth and increased testosterone.

community Creatine made all my high DHT symptoms return

82 upvotes 1 year ago

Creatine may increase DHT levels, potentially causing symptoms like acne, oily hair, and hair shedding. Users report mixed experiences, with some avoiding creatine due to hair loss concerns and others seeing no impact.

community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 1 year ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

community Creatine? Experiences?What say YOU?

6 upvotes 6 months ago

Creatine may cause hair shedding in some individuals, but there is no strong scientific evidence linking it to hair loss. Many users report personal experiences of increased hair loss with creatine, while others see no effect; OP is considering creatine while using finasteride and topical minoxidil for hair loss.

community Male pattern baldness is not cosmetic.

224 upvotes 9 months ago

Male pattern baldness is linked to health risks and should be treated medically. Finasteride is effective and should be insurance-covered.

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Learn

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learn zinc PCA

Can a zinc deficiency directly cause hair thinning or increased shedding? Studies link low serum zinc to diffuse shedding and alopecia areata, and severe deficiency states cause hair loss that reverses when zinc is replaced. The evidence is mostly observational, the one supplementation study was small and uncontrolled, and zinc is not a treatment for pattern hair loss.

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Clinics

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11
Hair Loss Treatments
Clínica SerumMérida, Yucatán · MX

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