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research 15809 Spironolactone use does not increase the risk of estrogen-dependent cancer recurrence: A retrospective analysis

November 2020 in “Journal of The American Academy of Dermatology”

This study investigated the use of spironolactone in patients with estrogen-dependent cancers, aiming to determine if it is linked to increased cancer recurrence risk, but results are not reported.

research 17β-Estradiol Increases APE1/Ref-1 Secretion in Vascular Endothelial Cells and Ovariectomized Mice: Involvement of Calcium-Dependent Exosome Pathway

9 citations , August 2021 in “Biomedicines”

This study found that 17β-estradiol was the most powerful hormone for inducing APE1/Ref-1 secretion in cultured vascular endothelial cells, with secretion occurring through exosomes dependent on estrogen receptors and intracellular calcium.

research Testosterone Induces Increase in Aquaporin (AQP)-1, 5, and 7 Expressions in the Uteri of Ovariectomized Rats

23 citations , July 2015 in “The Journal of Membrane Biology”

This study found that testosterone increased the expression of AQP-1, 5, and 7 in the uterus of rats, which may help explain the reduction in uterine fluid volume.

research Pubertal hormones increase hippocampal expression of α4βδ GABAA receptors

5 citations , February 2019 in “Neuroscience letters”

This study found that both declining levels of the neurosteroid THP and increasing levels of estradiol before puberty trigger maximal expression of α4βδ GABAA receptors in the CA1 hippocampus of female mice.

research STEROID HORMONES IN GERIATRICS

1 citations , February 1954 in “Journal of the American Geriatrics Society”

Steroid hormones can help treat aging issues and improve health in elderly people.

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Community Join

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community Finasteride has increased my Estradiol (estrogen) levels by 51% percentage

in Finasteride/Dutasteride 13 upvotes 1 year ago

Finasteride increased the user's estrogen levels by 51%, causing concerns about gynecomastia and sleep issues. Despite potential side effects, the user prefers continuing finasteride to prevent hair loss, considering it essential for self-esteem.

community Someone told me it is the increase in estradiol and estrogen from more free t that makes dht blockers work?

6 months ago

Finasteride and its effects on hair loss, with discussions on the role of estradiol and estrogen. Users debate whether increased estrogen from DHT blockers contributes to hair regrowth, with concerns about potential side effects like chemical castration.

community Is ED after taking Fin or Dut caused by less DHT or an increase in Estrogen/Estradiol

3 upvotes 2 years ago

Finasteride and dutasteride may cause erectile dysfunction due to reduced DHT, affecting nitric oxide and sexual function. Some suggest using aromatase inhibitors to address side effects, while others believe individual sensitivity to DHT reduction varies.

community High Estrogen and Test on Dut 5x a week

6 upvotes 1 year ago

A user experienced increased pimples and cysts after two years on dutasteride, possibly due to hormonal changes. Suggestions included seeing an endocrinologist, using supplements like boron and DIM, adjusting diet, and reducing body fat to manage side effects.

community Finasteride doubled my testosterone & estrogen

in Chat 265 upvotes 10 months ago

Finasteride increased testosterone and estrogen, stopped hair loss, and promoted regrowth. Users discussed side effects like libido changes and considered adding minoxidil and aromatase inhibitors.

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Learn

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learn Overview

learn Estradiol

an estrogen promoting hair regrowth more commonly used in women

learn Hair Transplant

Does a hair transplant increase hair density? A hair transplant can improve density, but results vary by individual factors.

learn vitamin b2

Can a deficiency in Vitamin B2 cause scalp irritation or increased hair shedding? Vitamin B2 deficiency can cause scalp irritation and may contribute to hair shedding.

learn zinc PCA

Can a zinc deficiency directly cause hair thinning or increased shedding? Studies link low serum zinc to diffuse shedding and alopecia areata, and severe deficiency states cause hair loss that reverses when zinc is replaced. The evidence is mostly observational, the one supplementation study was small and uncontrolled, and zinc is not a treatment for pattern hair loss.

learn Vascular Endothelial Growth Factor

Are there risks or side effects associated with treatments that increase Vascular Endothelial Growth Factor (VEGF)? Increasing VEGF can lead to risks like abnormal vessel growth and inflammation.

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