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Transgenic Mice Overexpressing CD109 in the Epidermis Display Decreased Inflammation and Granulation Tissue and Improved Collagen Architecture During Wound Healing

research Transgenic Mice Overexpressing CD109 in the Epidermis Display Decreased Inflammation and Granulation Tissue and Improved Collagen Architecture During Wound Healing

22 citations , February 2013 in “Wound Repair and Regeneration”

Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.

research Pathophysiology of the Burn Scar

10 citations , January 2018 in “Elsevier eBooks”

Burn scars heal abnormally and more research is needed to find better treatments.

research Skin Wounds in the MRL/MPJ Mouse Heal with Scar

51 citations , January 2006 in “Wound Repair and Regeneration”

MRL/MpJ mice's skin wounds heal with scars, unlike their ear wounds which can regenerate.

research Fibromodulin Reduces Scar Formation in Adult Cutaneous Wounds by Eliciting a Fetal-Like Phenotype

35 citations , October 2017 in “Signal Transduction and Targeted Therapy”

Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.

research Basic Concepts, Current Evidence, And Future Potential For Gene Therapy In Managing Cutaneous Wounds

6 citations , June 2019 in “Biotechnology Letters”

Gene therapy shows promise for improving wound healing, but more research is needed for human use.

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Community Join

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community People need to start accepting that only medical therapy (Fin/Dut) can save your hair in the long run.

in Treatment 112 upvotes 1 year ago

Minoxidil can regrow hair but doesn't address the underlying issue of DHT, leading to continued hair loss. Users discuss their experiences with finasteride and dutasteride, mentioning side effects, personal outcomes, and alternatives like microdosing topical finasteride.

community Progress o regress? 2 Years only dermaroller (and RU for only 2 month)

in Is this regrowth? 70 upvotes 2 years ago

The conversation discusses hair loss and treatments, with users suggesting the original poster's hair has receded despite using a dermaroller and RU58841 for two months. Many recommend starting finasteride and minoxidil for better results.

community Verteporfin mixing solute for transplants

in Treatment 12 upvotes 1 year ago

Doctors are testing verteporfin topically for healing and potential regeneration after transplants. The user is asking how it is formulated for topical use, such as if it's mixed with a carrier gel.

community Microneedling at .25 everyday before applying Min

in Minoxidil 26 upvotes 6 months ago

Daily microneedling at 0.25mm before applying minoxidil is debated, with some suggesting weekly microneedling is safer and more effective. Concerns include potential skin damage and systemic absorption, while alternatives like tretinoin are considered safer for enhancing minoxidil absorption.

community HT / Meds results are reverting, thinning, crazy shedding..

in Progress Pictures 163 upvotes 11 months ago

A user experienced significant hair shedding and thinning 10 months post-hair transplant despite using minoxidil and topical finasteride. They are considering switching to oral finasteride or dutasteride and are also dealing with scalp conditions like seborrheic dermatitis.

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