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GlossaryImmunohistochemical Methods

use antibodies to detect specific proteins in tissue samples

Immunohistochemical Methods, often abbreviated as IHC Methods, are laboratory techniques used to visualize specific proteins or antigens in tissue samples. By applying antibodies that bind to these targets and then using a color change or fluorescent marker, scientists and medical professionals can identify the presence and distribution of particular molecules, aiding in disease diagnosis and research.

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research Immunohistochemical Localization of TGF-β in Alopecia Areata

July 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

TGF-β is found in hair follicles and may cause hair loss in alopecia areata.

research A Practical Guide for the Study of Human and Murine Sebaceous Glands In Situ

56 citations , September 2013 in “Experimental Dermatology”

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

research Comment on Scalp Neuropathy in Androgenetic Alopecia

1 citations , April 2022 in “Journal of The American Academy of Dermatology”

Hair loss in men (androgenetic alopecia) is significantly linked to decreased scalp sensitivity, but not temperature sensitivity. More research is needed to confirm this. Comparing this hair loss to leprosy is unsupported and stigmatizing.

research Cytokeratin 19 Expression in Common Skin Carcinomas

January 2003 in “The Chinese Journal of Burns Wounds & Surface Ulcers”

CK 19 expression is higher in more severe skin cancers.

research Microtubule Associated Protein 2 Expression Defines the Companion Layer of the Anagen Hair Follicle and an Analogous Zone in the Nail Unit

14 citations , October 2002 in “Journal of cutaneous pathology”

MAP-2 is crucial for the structure of hair follicles and nails.

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community DHT Harms Scalp Microbiome: DHT Itch is REAL

in Research/Science 413 upvotes 7 months ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 673 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Another clueless guy fearmongering and spreading misinformation

in Chat 251 upvotes 1 year ago

The conversation discusses hair loss treatments, with some users advocating for finasteride and minoxidil, while others express concerns about potential side effects of finasteride. A social media influencer is criticized for promoting scalp massages and minoxidil over finasteride, which some believe is misinformation.