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GlossaryImmunostaining (immunofluorescent staining)

technique using antibodies to detect specific proteins in tissues

Immunofluorescence (IF) is a laboratory technique used to visualize the presence and location of specific proteins or antigens in cells or tissue sections by using antibodies that are chemically linked to a fluorescent dye. When these antibodies bind to their target, the fluorescent dye can be seen under a microscope with the appropriate light, allowing researchers to study the distribution and abundance of the proteins of interest.

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research SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin

225 citations , April 2018 in “Journal of Investigative Dermatology”

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

research The Inconsistent Regulation of HOXC13 on Different Keratins and the Regulation Mechanism on HOXC13 in Cashmere Goat (Capra Hircus)

17 citations , August 2018 in “BMC Genomics”

The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.

research Comparison of Growth Status of Epithelial Stem Cells Derived from Plucked Hair Follicle Between Different Culture Conditions

January 2009 in “Journal of Jilin University”

3T3 fibroblasts feeder is best for growing epithelial stem cells from hair follicles.

research Lichen Planopilaris: A Rare Inflammatory Cicatricial Alopecia

April 2012 in “Informa Healthcare eBooks”

Lichen planopilaris is a rare, chronic condition causing hair loss, mainly in middle-aged women, and early treatment is important to prevent permanent baldness.

research Lineage Tracing of Hair Follicle Stem Cells in Epidermal Whole Mounts

11 citations , January 2013 in “Methods in molecular biology”

The method allows for 3D tracking of hair follicle stem cells and shows they can regenerate hair for up to 180 days.

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