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GlossaryImmunostaining (Immunofluorescence)

technique using antibodies to detect specific proteins in tissues

Immunofluorescence (IF) is a laboratory technique used to visualize the presence and location of specific proteins or antigens in cells or tissue sections by using antibodies that are chemically linked to a fluorescent dye. When these antibodies bind to their target, the fluorescent dye can be seen under a microscope with the appropriate light, allowing researchers to study the distribution and abundance of the proteins of interest.

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research Clinicopathological Study of Discoid Lupus Erythematosus

March 2009

Discoid Lupus Erythematosus is more common in women aged 31-40, often worsened by sunlight, and confirmed by specific lab tests.

research Recurrence of Pemphigus Vulgaris Associated With Interleukin 2 Therapy

25 citations , July 1994 in “Archives of Dermatology”

A man's skin condition, pemphigus vulgaris, came back after he was treated with interleukin 2 for cancer.

research Histopathologic Spectrum of Alopecia

February 2007

Combining vertical and horizontal sectioning improves scalp biopsy analysis for alopecia.

research Serial Cultivation of Human Scalp Hair Follicle Keratinocytes

14 citations , July 1983 in “Acta Dermato Venereologica”

A method was developed to grow millions of hair cells from a single hair for research and storage.

research Identification of Human Hair Follicle Antigens Targeted in the Presumptive Autoimmune Hair Follicle Disorder Alopecia Areata and Their Potential Functional Relevance In Vitro: Methods Development for Isolation and Identification of Alopecia Areata-Relevant Human Hair Follicle Antigens Using a Proteomics Approach and Their Functional Assessment Using an Ex Vivo Hair Follicle Organ Culture Model

January 2008 in “Bradford Scholars (University of Bradford)”

Alopecia areata may be caused by antibodies targeting specific hair follicle proteins, hindering hair growth.

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