research Trichoblastic Carcinoma (“Malignant Trichoblastoma”) with Lymphatic and Hematogenous Metastases
Long-standing benign tumors can become cancerous, especially in people with weakened immune systems.
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5 / 1000+ results research O05 Distinct epidermal cell populations and single-cell gene expression signatures are associated with Staphylococcus aureus in atopic dermatitis
In this study, distinct immune and cellular profiles were observed in adults with atopic dermatitis associated with high levels of Staphylococcus aureus, including increased proinflammatory T cells and markers of skin barrier impairment, pointing to potential therapeutic targets for managing these interactions.
research Skin Barrier Dysfunction in Acne Vulgaris: Pathogenesis and Therapeutic Approaches
This review discusses the mechanisms of skin barrier impairment in acne vulgaris and suggests strategies for its repair but reports no new clinical results.
research Great Expectations: Induced pluripotent stem cell technologies in neurodevelopmental impairments
This article reviews the development and use of induced pluripotent stem cell models and artificial organoids for studying neurodevelopmental disorders, but it reports no new clinical findings.
research Neuroprotective and immunomodulatory effects of human hair follicle stem cells on streptozotocin-induced memory impairment in rats: insights into inflammation and neurotrophic mechanisms
This study found that treating male rats with human hair follicle stem cells improved memory function impaired by streptozotocin and increased both neurotrophic and inflammatory markers, suggesting potential neuroprotective effects in this model.
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5 / 266 resultscommunity If PP405 goes systemic this would be quite catastrophic
Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.
community if Post Finasteride Syndrome is real. Why is it only the negative effects and not positive have log term effect?
Finasteride is used for hair loss, with mixed reports of no side effects and claims of long-term negative effects known as Post Finasteride Syndrome (PFS). The conversation debates the existence and causes of PFS, with differing opinions on whether it is psychological or real.
community Finasteride does deplete important nuero-active steroids
Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.
community The EU has Finasteride and Dutasteride under review at risk of getting banned.
Finasteride and Dutasteride are under review in the EU due to concerns about side effects like depression, but they are unlikely to be banned. Access to these medications varies, with easier availability in the UK compared to some EU countries.
community Attention Finasteride / Dutasteride and Your liver
Finasteride may cause elevated liver enzymes, potentially leading to liver issues, though this is rare. Users should monitor liver function and consider topical alternatives if liver sensitivity occurs.
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1 / 801 results- Tried everything and still getting bald patches? Procapil may help calm the immune response Procapil is a cosmetic ingredient complex; laboratory studies of its individual ingredients report anti-inflammatory effects, but no published clinical trial has tested it in alopecia areata or any other immune-related hair loss. Spreading bald patches should be assessed by a dermatologist.
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