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research Interleukin-6 Null Mice Paradoxically Display Increased STAT3 Activity and Wound-Induced Hair Neogenesis

16 citations , January 2016 in “Journal of Investigative Dermatology”

This study found that IL-6 knockout mice exhibited increased wound-induced hair neogenesis compared to wild-type mice, likely due to enhanced STAT3 activation facilitated by compensatory cytokine activity.

research Screening for Anti-inflammatory Activities in Extracts from Korean Herb Medicines

14 citations , March 2014 in “Journal of the Society of Cosmetic Scientists of Korea”

This study suggests that ethanol extracts from ten selected Korean herb medicines reduced inflammatory markers in a cell model and did not cause skin irritation in human testing, indicating potential cosmetic use for irritation prevention.

research Clinical Features and Treatment Options of Vogt-Koyanagi-Harada Disease

2 citations , May 2025 in “IntechOpen eBooks”

This article highlights that early and high-dose corticosteroid therapy, along with immunosuppressive agents, is crucial for managing Vogt-Koyanagi-Harada disease, and emerging biological therapies may benefit refractory cases.

research Downregulation of nuclear factor-kappaB activation in human keratinocytes by melanogenesis inhibitors

May 2004 in “International Journal of Cosmetic Science”

This study found that kojic acid and niacinamide were the most effective inhibitors of UVB-induced NF-κB activation and IL-6 secretion in HaCaT keratinocytes, suggesting a role in modulating melanotrophic factor synthesis.

Increased Expression of Nerve Growth Factor and Neurokinin-1 Alarm the Hair Loss in Females with Trichodynia

research Increased expression of nerve growth factor and neurokinin-1 alarm the hair loss in female with trichodynia

March 2012 in “Journal of The American Academy of Dermatology”

Higher levels of certain nerve-related proteins are linked to hair loss in women with scalp pain.

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Learn

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learn Hair Transplant

Do I need to shave my head for a hair transplant? Shaving your head is not always necessary for a hair transplant.
Is a hair transplant permanent? Transplanted hair is generally permanent but requires ongoing care to maintain results.
How long does recovery take after a hair transplant? Recovery after a hair transplant typically takes 7 to 14 days for initial healing.
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learn Scalp Micropigmentation

How long does Scalp Micropigmentation last, and does it need touch-ups over time? Scalp micropigmentation lasts 2 to 8 years and requires touch-ups every 1 to 5 years.

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Community Join

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community 3 months on finasteride and hair density IS decreasing

in Finasteride/Dutasteride 43 upvotes 5 months ago

Finasteride can cause initial hair shedding as part of the treatment process, which is normal and often leads to regrowth of healthier hair. Users discuss experiencing multiple shedding phases and emphasize patience, as results can take several months to become noticeable.

community Finasteride alternative close to fda approval in the US

60 upvotes 3 months ago

Breezula, a topical treatment, is anticipated to be available in the US by mid-2027 as a potential alternative to finasteride with fewer systemic side effects. There is ongoing debate about its effectiveness and some users report similar side effects to finasteride.

community Solving Hair Loss with Research at MIT

in Research/Science 595 upvotes 1 year ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community After 6 Months adding Topical Fin to minoxidil. Trust the process, be patient!

in Progress Pictures 127 upvotes 1 year ago

After 6 months of adding topical finasteride to minoxidil, the user saw significant hair improvement, with noticeable results starting from the 5th month. The treatment included 5% minoxidil, 0.5 mg topical finasteride, and supplements like omega-3, minerals, and vitamins, with minimal side effects reported.

community 6 months on minoxidil shedding again

269 upvotes 5 months ago

A user experienced hair shedding after six months of using topical minoxidil and is considering adding finasteride to their routine. Many suggest that minoxidil alone is insufficient for stopping hair loss and recommend combining it with finasteride or dutasteride for better results.

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Experts

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All 182 expert results →