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research From Bald to Bold: Reversal of Alopecia Totalis in an Adolescent Using Dupilumab Monotherapy

February 2026 in “Journal of Drugs in Dermatology”

This case study reports on a 13-year-old male with alopecia totalis who experienced successful hair regrowth after being treated with dupilumab, an interleukin-4 and IL-13 antagonist, suggesting its potential utility in managing alopecia areata in pediatric patients with comorbid atopic dermatitis.

research The use of dupilumab for the treatment of alopecia areata

November 2024 in “Dermatology Online Journal”

Dupilumab may help treat alopecia areata, but more research is needed.

research Central Opioid Inhibition of Neuroendocrine Stress Responses in Pregnancy in the Rat Is Induced by the Neurosteroid Allopregnanolone

123 citations , May 2009 in “Journal of Neuroscience”

In this study, researchers found that in late pregnancy, the neuroactive progesterone metabolite allopregnanolone inhibits HPA axis responses to immune challenges via an opioid-mediated mechanism.

research ACTH as first line treatment for acute calcium pyrophosphate crystal arthritis in 14 hospitalized patients

14 citations , June 2013 in “Joint Bone Spine”

This review discusses current anti-inflammatory treatment options for calcium pyrophosphate crystal deposition disease (CPPD) and highlights the lack of crystal-targeted therapies, emphasizing the need for more research to guide treatment.

research Cytostatics and immunosuppressive drugs

January 1989 in “Side effects of drugs annual”

This chapter reviews studies on the side effects of cytostatics and immunosuppressive drugs, detailing various toxicities such as cardiovascular, pulmonary, and neurotoxicity, but provides no new clinical results.

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Community Join

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community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

29 upvotes 2 months ago

Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

community The Real Cause Of Androgenetic Alopecia

675 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Solving Hair Loss with Research at MIT

in Research/Science 595 upvotes 1 year ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

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Learn

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learn Hair Transplant

Is a hair transplant permanent? Transplanted hair usually lasts long term, but it is not guaranteed and the hair around it can keep thinning, so the overall result can change with time.
When can I exercise after a hair transplant? Avoid strenuous exercise for at least 1 month after a hair transplant.
Can women get hair transplants? Some women are candidates for a hair transplant, but diffuse thinning and a thin donor area limit who is suitable. Clinics say a careful assessment of the cause comes first.
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Experts

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74
Hair Loss Specialist
Will Quaye
Crawley, England, United Kingdom

Clinics

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Will Quaye