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GlossaryInterleukin-4 (IL4)

protein that regulates immune responses and inflammation

Interleukin-4 (IL-4) is a type of protein called a cytokine that plays a crucial role in the immune system. It helps regulate the balance of immune responses by promoting the growth and differentiation of certain white blood cells, particularly those involved in allergic reactions and asthma. IL-4 is also involved in the regulation of antibody production, making it important for both immune defense and inflammation.

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research Controlled Delivery of T-box21 Small Interfering RNA Ameliorates Autoimmune Alopecia in a C3H/HeJ Mouse Model

69 citations, February 2008 in “The American journal of pathology”

Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.

3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling

research 3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling

26 citations, October 2016 in “Biomolecules & Therapeutics”

3-Deoxysappanchalcone helps human hair cells grow and stimulates hair growth in mice by affecting certain cell signaling pathways.

ADM Scaffolds Generate a Pro-Regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1

research ADM Scaffolds Generate a Pro-Regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1

17 citations, June 2018 in “Frontiers in Physiology”

ADM scaffolds help skin heal by promoting a healing-type immune response.

research Dupilumab And Alopecia: A Janus Effect

29 citations, July 2019 in “Dermatologic Therapy”

Dupilumab can both heal and cause hair loss.

Safety of Biological Therapies for Severe Asthma: An Analysis of Suspected Adverse Reactions Reported in the WHO Pharmacovigilance Database

research Safety of Biological Therapies for Severe Asthma: An Analysis of Suspected Adverse Reactions Reported in the WHO Pharmacovigilance Database

1 citations, March 2024 in “BioDrugs”

Biologics for severe asthma have known side effects, but some new risks need more study.

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