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GlossaryInterleukin-36 (IL36)

group of cytokines involved in immune system signaling and inflammation

Interleukin-36 (IL-36) is a group of cytokines, which are small proteins important for cell signaling in the immune system. These cytokines play a crucial role in inflammatory responses and are involved in the pathogenesis of various autoimmune and inflammatory diseases, such as psoriasis. IL-36 includes three agonists (IL-36α, IL-36β, and IL-36γ) and an antagonist (IL-36Ra), which together help regulate the body's immune response.

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research Clinical and Genetic Aspects of Alopecia Areata: A Cutting Edge Review

1 citations, June 2023 in “Genes”

Hair loss from Alopecia Areata is caused by both genes and environment, with several treatments available but challenges in cost and relapse remain.

research Modulating Embryonic Signaling Pathways Paves the Way for Regeneration in Wound Healing

February 2024 in “Frontiers in physiology”

Modifying certain signals in the body can help wounds heal without scars and regrow hair.

research Biocompatible Nanoparticles and Vesicular Systems in Transdermal Drug Delivery for Various Skin Diseases

151 citations, November 2018 in “International Journal of Pharmaceutics”

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

research Hidradenitis Suppurativa and Comorbid Disorder Biomarkers, Druggable Genes, New Drugs and Drug Repurposing—A Molecular Meta-Analysis

15 citations, December 2021 in “Pharmaceutics”

The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.

research Transcriptome Meta-Analysis Confirms the Hidradenitis Suppurativa Pathogenic Triad: Upregulated Inflammation, Altered Epithelial Organization, and Dysregulated Metabolic Signaling

13 citations, September 2022 in “Biomolecules”

The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.

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