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Neutralization of IL-8 Prevents Dermatologic Adverse Events Associated with Epidermal Growth Factor Receptor Inhibition

research Neutralization of IL-8 Prevents the Induction of Dermatologic Adverse Events Associated with the Inhibition of Epidermal Growth Factor Receptor

32 citations , June 2012 in “PLoS ONE”

This study found that locally injected zalutumumab in healthy volunteers induced a papulopustular rash similar to systemic EGFR inhibitors, and that IL-8 inhibition reduced this dermatological side effect.

research Distribution of human B-defensin 2, TNF-alpha, IL-1 alpha, IL-6 and IL-8 in psoriatic skin

1 citations , December 2012 in “Papers on Anthropology”

This study found that psoriatic skin lesions commonly express the cytokines IL-6, IL-8, and TNF-alpha along with a moderate presence of the antimicrobial protein defensin.

IL-9 Mediated Human Primary Keratinocytes Invasion Is Dependent on MLC Controlled Contractility and Independent of MMP Activity

research 879 IL-9 mediated human primary keratinocytes invasion is dependent on MLC controlled contractility and independent of MMP activity

April 2018 in “Journal of Investigative Dermatology”

This study found that IL-9 influences the behavior of human primary keratinocytes by promoting motility while reducing invasion potential through a novel mechanism independent of matrix-metalloproteinases.

research 809 IL-13 protein concentrates in the epidermis of lesional and non-lesional skin of AD patients

July 2024 in “Journal of Investigative Dermatology”

IL-13 protein is much higher in the skin of atopic dermatitis patients than in healthy skin.

research 1349 Stimulation of hair follicle stem cell proliferation through an IL-1α dependent activation of γδT-cells

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

In this study, IL-1α and IL-7 were found to work together to activate epidermal γδ T-cells, which in turn promote hair follicle stem cell proliferation during mouse wound healing.

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Learn

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learn Scalp Micropigmentation

Will anyone notice my scalp micropigmentation treatment? Scalp micropigmentation is designed to be undetectable when done correctly.
How should you care for your scalp after Scalp Micropigmentation to keep the results looking natural? Avoid sweating, sun exposure, and washing for 3-7 days after scalp micropigmentation.

learn Hair Transplant

Is a hair transplant painful? A hair transplant is generally comfortable due to local anesthesia, with mild post-procedure soreness possible.
What happens after a hair transplant? Expect mild swelling and redness, with new hair growth starting in 3 to 6 months.
Do hair transplants look natural? When done correctly, hair transplants can look completely natural and undetectable.

learn Redensyl

commercial product with a blend of mostly natural ingredients for hair regrowth

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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Community Join

5 / 120 results

community Il PP405 è molto promettente ma non è l'unico in grado di liberarci dalla iattura

3 upvotes 1 year ago

PP405 shows promise in hair loss treatment, but stem cell therapy using adipose-derived stem cells and ATP also successfully reversed androgenetic alopecia in mice. Stem cell therapy is costly, and some doubt the effectiveness of PP405 based on press releases.

community 8 years of hair loss, turning 30 next month

in Progress Pictures 151 upvotes 1 year ago

The user has been dealing with hair loss for 10 years, worsened by psoriasis, and uses minoxidil and finasteride. They seek advice on managing psoriasis and hair loss, with suggestions to see a dermatologist, try different shampoos, and be patient.

community Progression après 8 mois Finastéride/Dutastéride/Minoxidil

143 upvotes 5 months ago

The user shared their hair loss treatment progress using Finasteride, Dutasteride, and Minoxidil, noting initial irritation with topical Minoxidil and experiencing shedding phases. They reported no side effects and encouraged others to try this regimen for alopecia.

community Before and after: 1 year of Min, 8 months of Fin

355 upvotes 4 months ago

Improved hair density and texture after using 1mg oral finasteride and 5mg oral minoxidil for a year. The user is satisfied with the results, noting no significant side effects except reduced seminal volume.

community Kintor long term safety phase 3

in Research/Science 66 upvotes 1 year ago

Kintor's phase III trial for pyri (KX-826) showed promising safety and efficacy results, with no drug-related sexual dysfunction reported. Users discussed their experiences with pyri, Minoxidil, Dutasteride, and concerns about the validity of the study results.

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