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This case report details a rare instance of simultaneous onset of systemic lupus erythematosus and IgG4-related disease in a 73-year-old woman, where treatment improved symptoms by using high-dose glucocorticoids, hydroxychloroquine, and belimumab.

In this case report, a young Japanese man was diagnosed with scalp IgG4-related disease, which mimicked acne keloidalis nuchae but was identified by histopathology and elevated serum IgG4 levels as a systemic fibroinflammatory disorder, highlighting the importance of differential diagnosis in atypical scarring alopecia.

This report identifies a novel splice-site variant in the LAMB3 gene linked to junctional epidermolysis bullosa, emphasizing the need for gene sequencing in diagnosing the disease.

In this report, an 80-year-old male with elevated serum IgG4 presented with a lesion suggestive of IgG4-related ophthalmic disease, but lack of orbital imaging and biopsy precluded definitive diagnosis, highlighting the necessity of excluding similar conditions before long-term treatment.

ASLAN004 was safe and well-tolerated, supporting further development for treating certain diseases.