314 citations
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April 2010 in “Developmental Cell” β-catenin in the dermal papilla is crucial for normal hair growth and repair.
5 citations
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February 2019 in “PloS one” Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.
January 2021 in “Journal of cosmetology & trichology” L-(+)-Tartaric Acid may help increase certain hair growth genes without harming cells.
September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Different fish use the same genes to regrow teeth.
6 citations
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January 2014 in “Genetics and Molecular Research” The study focused on the construction of a hair follicle-specific expression vector for IGFBP-5 in Inner Mongolia Cashmere goat fetal fibroblasts. Researchers created a vector, pCDsRed2-K-IGFBP5, by cloning IGFBP-5 downstream of the KAP6-1 promoter and inserting it into a vector containing a red fluorescent protein. This vector was transfected into goat fetal fibroblast cells using Lipofectamine 2000, and stable cell clones expressing red fluorescence were selected with Geneticin. Polymerase chain reaction confirmed the stable integration of the transgene. The findings indicated that this method was effective for constructing hair follicle-specific expression vectors and obtaining stable transfection donor cells for nuclear transfer.