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Janus Kinase Inhibition in Down Syndrome: Two Cases of Therapeutic Benefit for Alopecia Areata

research Janus kinase inhibition in Down syndrome: 2 cases of therapeutic benefit for alopecia areata

32 citations , April 2019 in “JAAD case reports”

This study discusses the immune dysregulation observed in individuals with Down syndrome, highlighting their increased risk for autoimmune skin conditions, but does not yet clarify the molecular mechanisms behind this profile.

Analysis of Gene Expression in Isolated Single Hair Follicles Using Semiquantitative Reverse-Transcriptase Polymerase Chain Reaction

research Analysis of Gene Expression in Isolated Single Hair Follicles: An Approach Using Semiquantitative Reverse-Transcriptase—Polymerase Chain Reaction

May 1995 in “Journal of Investigative Dermatology”

Researchers developed a new way to measure gene activity in single hair follicles and found that a specific gene's activity changes with different amounts and times of treatment.

Effect of Diode Pumping Solid State Laser with Wavelength 589 nm on Gene Expression of Interleukin-2 and Interferon-Gamma in Human T-Lymphocytes

research Effect of diode pumping solid state laser with wavelength 589 nm on gene expression of interlukine-2 and interferon-gamma Lowercase in human T-lymphocytes

September 2024 in “Journal of the Pakistan Medical Association”

In this experimental study, laser irradiation significantly altered the gene expression of cytokines in cultured human T-cell lymphocytes, suggesting that such laser light may photobiomodulate cytokine production in vitro.

research An immune regulatory CCT repeat containing oligodeoxynucleotide capable of causing hair loss in male mice

January 2016 in “Human & Experimental Toxicology”

This study reported that CCT oligodeoxynucleotide induced patchy hair loss in male mice with specific genetic traits, suggesting gender and genetic preferences in immune response.