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GlossaryInterferon-alpha (IFN-alpha)

protein that boosts immune response against viruses and cancer

Interferon-alpha (IFN-α) is a type of protein produced by the body's immune system in response to viral infections. It helps to inhibit viral replication and modulate the immune response, making it a crucial component in the body's defense against pathogens. Clinically, IFN-α is used in the treatment of various conditions, including certain types of cancer and viral infections like hepatitis C.

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Exacerbation of Alopecia Areata During Pegylated Interferon Alpha-2b and Ribavirin Therapy, Possibly Due to the Collapse of Hair Follicle Immune Privilege

research Exacerbation of Alopecia Areata During Pegylated Interferon Alpha-2b and Ribavirin Therapy, Possibly Due to the Collapse of Hair Follicle Immune Privilege

10 citations, September 2014 in “European Journal of Dermatology”

A woman's hair loss worsened after starting hepatitis C treatment due to immune changes in her hair follicles.

research The Influence of Interferon on Healthy and Diseased Skin

32 citations, December 2018 in “Cytokine”

Type I interferons play a key role in the development of various skin diseases.

research Reply

2 citations, December 1997 in “Journal of The American Academy of Dermatology”

The document concludes that doctors should monitor children's brain development when treating hemangiomas with interferon alfa and consider stopping the treatment if problems arise, while also exploring drugs that might counteract side effects.

research Case Report: Diffuse Hypertrichosis in the Course of Hepatitis C Treatment by IFN-Alpha and Ribavirin

16 citations, August 2002 in “Journal of Interferon and Cytokine Research”

A man developed excessive hair growth after treatment with interferon-alpha and ribavirin for hepatitis C.

research Widespread Dystrophic-Anagen Alopecia and Drug Eruption Due to Usage of PEG-IFN Alpha-2a/Ribavirin Combination Therapy

1 citations, January 2014 in “Hair therapy & transplantation”

The combination therapy of PEG-IFN α-2a and Ribavirin can cause widespread hair loss and skin reactions.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 864 upvotes 4 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Verteporfin and Microneedling

in Treatments 8 months ago

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

community Fevipiprant 2019!

17 upvotes 8 years ago

The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.