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GlossaryInvolutional Follicular Erosion (IFE)

gradual thinning and weakening of hair follicles with aging

Involutional Follicular Erosion (IFE) refers to the gradual thinning and weakening of hair follicles that occurs naturally with aging. This process leads to a reduction in hair density and can contribute to age-related hair loss.

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research Serum Ferritin Levels Among Individuals With Androgenetic Alopecia in Ile-Ife, Nigeria

October 2022 in “PubMed”

People with early onset hair loss (Androgenetic Alopecia) in Ile-Ife, Nigeria, have significantly lower iron levels compared to those with adult-onset hair loss.

Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition

research Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition

174 citations, November 2016 in “Cell stem cell”

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

research An Extended Epidermal Response Heals Cutaneous Wounds in the Absence of a Hair Follicle Stem Cell Contribution

170 citations, November 2007 in “The journal of investigative dermatology/Journal of investigative dermatology”

Skin can heal wounds without hair follicle stem cells, but it takes a bit longer.

research Lineage Analysis of Epidermal Stem Cells

57 citations, January 2014 in “Cold Spring Harbor Perspectives in Medicine”

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

research Hair Follicle and Interfollicular Epidermal Stem Cells Make Varying Contributions to Wound Regeneration

47 citations, September 2015 in “Cell Cycle”

Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.

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community Shedding on finasteride only; looking for motivation

in Finasteride/Dutasteride 15 upvotes 8 months ago

A user started finasteride for hair loss and saw improvement, but is now experiencing shedding and thinning in new areas. They added Nizoral due to dandruff caused by finasteride. Replies suggest that shedding is normal around 6 months and advise to stick with the treatment.