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This study evaluated the effects of exosome therapy from hypoxia-treated mesenchymal stem cells on a fluconazole-induced alopecia model in rats and found that it significantly reduced TNF-α and increased VEGF levels, suggesting potential as a novel regenerative treatment for alopecia.

This study demonstrated that a new biomimetic tissue engineering strategy using DP spheroids with vascularization significantly restored the hair-inducing properties of dermal papilla cells compared to traditional 3D cultures.

In this study, topical administration of secretome hypoxia mesenchymal stem cells gel increased IL-10 and decreased TNF-α gene expression in a fluconazole-induced alopecia-like model in rats, with the 40 μL dose having the most significant effect.

This study suggests that administering SH-MSCs gel might decrease IL-6 expression and increase TGF-β expression in alopecia-like rats, indicating potential for alopecia therapy.

This study reports that γ-ray exposure in rats led to dermal endothelial proliferation, new vessel formation around hair follicles, and increased inflammatory markers, suggesting possible early stimulatory effects on hair growth.