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GlossaryHypogonadism

condition where sex glands produce insufficient hormones

Hypogonadism is a medical condition where the body's sex glands, the testes in men and the ovaries in women, produce little or no hormones. This can lead to various symptoms such as reduced libido, infertility, and in some cases, hair loss. It can be caused by genetic factors, injury, or certain medical conditions, and often requires hormone replacement therapy for management.

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research Original Research—Endocrinology: Comparison of the Steady-State Pharmacokinetics, Metabolism, and Variability of a Transdermal Testosterone Patch Versus a Transdermal Testosterone Gel in Hypogonadal Men

38 citations , February 2005 in “The journal of sexual medicine”

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

research Oral Testosterone With and Without Concomitant Inhibition of 5α-Reductase by Dutasteride in Hypogonadal Men for 28 Days

11 citations , December 2010 in “The Journal of Urology”

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

research Clinical Improvements in Erectile Function and Mood in Hypogonadal Men Treated with 4.5% Nasal Testosterone Gel (Natesto)

February 2018 in “The Journal of Sexual Medicine”

Natesto nasal gel improves erectile function and mood in men with low testosterone within 30 days.

research Cognitive Effects of Testosterone and Finasteride Administration in Older Hypogonadal Men

August 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)”

Testosterone and finasteride showed minor cognitive benefits in older men.

research New Biomarkers to Evaluate Hyperandrogenemic Women and Hypogonadal Men

14 citations , January 2018 in “Advances in Clinical Chemistry”

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

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community Creatine is the opposite of minoxidil !

in Research/Science 320 upvotes 1 month ago

Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.

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