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This review discusses hypopituitarism's bidirectional relationship with COVID-19 due to metabolic comorbidities and pituitary risks, but it reports no new clinical results.

This report describes a case of a 75-year-old woman whose diagnosis of hypopituitarism led to significant weight gain and improved physical function with treatment, highlighting the potential for overcoming frailty when investigating underlying causes in elderly patients.

In this case report, the researchers observed that combining growth hormone therapy with the biologic drug dupilumab effectively improved growth and health outcomes in a patient with Netherton syndrome and comorbid hypopituitarism, suggesting a multidisciplinary approach may be beneficial for managing such cases.

This case report highlights that Sheehan syndrome, though rare in developed countries, can occur and underscores the importance of detailed history taking to uncover the cause of atypical presentations.

In this case study, a 68-year-old woman was diagnosed with central diabetes insipidus and hypothalamic hypopituitarism due to a Rathke's cleft cyst.