April 2017 in “The journal of sexual medicine” This study investigated the effects of 5-alpha-reductase inhibitors on penile histomorphometry in both normotensive and hypertensive rats, reporting no significant changes between treated and untreated groups.
April 2017 in “The Journal of urology/The journal of urology” This study found that Sonic Hedgehog protein treatment enhanced the sprouting and regeneration of pelvic ganglia and cavernous nerves after injury, with localization of delivery affecting outcomes.
In this study, testosterone treatment was found to increase blood pressure in rats, potentially through mechanisms involving sodium and water retention in the kidneys and changes in specific gene expressions in the brain.
January 2024 in “Life sciences” This study observed that in spontaneously hypertensive rats, testosterone's effects on endothelium-dependent vasodilation involved reduced nitric oxide levels, increased oxidative stress, and greater reliance on endothelium-dependent hyperpolarization, with variations in these responses noted when testosterone was combined with either anastrozole or finasteride.
17 citations
,
April 1972 in “PubMed” Minoxidil lowers blood pressure and spreads throughout the body in normal rats.