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GlossaryDrug Reaction with Eosinophilia and Systemic Symptoms (Drug Hypersensitivity Syndrome)

severe allergic reaction to medication causing rash and organ damage

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) is a severe, potentially life-threatening hypersensitivity reaction to certain medications. It is characterized by a widespread skin rash, fever, swollen lymph nodes, and involvement of internal organs such as the liver, kidneys, and lungs. Eosinophilia, an elevated level of a type of white blood cell called eosinophils, is a hallmark of this condition. Early recognition and discontinuation of the offending drug are crucial for managing DRESS.

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research Novel Insights Into the Molecular Mechanisms Underlying Generalized Glucocorticoid Resistance and Hypersensitivity Syndromes

15 citations, July 2017 in “Hormones”

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

research Primary Generalized Glucocorticoid Resistance And Hypersensitivity

48 citations, January 2011 in “Hormone Research in Paediatrics”

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

research Non-Canonical Dimerization of the Androgen Receptor and Other Nuclear Receptors: Implications for Human Disease

25 citations, June 2019 in “Endocrine Related Cancer”

Mutations in certain receptors can cause diseases and offer new treatment options.

research A Case of Hyperpigmentation and Acanthosis Nigricans by Testosterone Injections

6 citations, February 2014 in “Human & experimental toxicology”

Testosterone injections can cause skin darkening and thickening.

research Spectrum of Pediatric Dermatoses in a Private Medical College

September 2023 in “Journal of Nepal Paediatric Society”

Skin infections and rashes are the most common skin problems in children.

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community I really wish I started Propecia sooner

in Finasteride/Dutasteride 1 year ago

A 27-year-old man's experience with taking Finasteride to treat hair loss and the positive side effects he has experienced, such as improved skin. The user also shared their journey of how they were scared away from taking Finasteride due to fear of possible side effects before eventually deciding to take it.

community Why is Kevin Mann (Haircafe) Hated?

in Chat 62 upvotes 1 year ago

Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.

community Fin isn’t working anymore after 3 years, afraid to switch to dut?

in Finasteride/Dutasteride 27 upvotes 4 months ago

Finasteride stopped working for a user after 3 years, and they are considering switching to dutasteride. Other users suggest trying dutasteride, with some sharing positive experiences and additional treatments like minoxidil and RU58841.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 9 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community Eliminating scalp itch leads to regrowth (and my RU58841 progress)

in Research/Science 63 upvotes 1 year ago

User experienced hair regrowth after eliminating scalp itch with RU58841. Others discussed itch and hair loss connection, and effectiveness of combining RU58841 with 5AR inhibitors.

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