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GlossaryHyperpigmentation (Hyperpigmented Skin)

condition where skin patches darken due to excess melanin

Hyperpigmentation is a condition where patches of skin become darker than the surrounding areas due to an excess production of melanin, the pigment responsible for skin color. This can be caused by factors such as sun exposure, inflammation, hormonal changes, or certain medications, and is commonly seen in conditions like melasma, age spots, and post-inflammatory hyperpigmentation.

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research Mucocutaneous Manifestations of Endocrine Disorders

November 2013 in “John Wiley & Sons, Ltd eBooks”

Skin symptoms can indicate endocrine disorders and have various treatments.

research Photobiomodulation for Skin Pigmentation Disorders: A Dual-Function Treatment

2 citations, May 2023 in “Photobiomodulation, photomedicine, and laser surgery”

Light therapy is effective and safe for treating skin color disorders like vitiligo and dark spots.

[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs

research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs

26 citations, July 2007 in “Biochemical Pharmacology”

ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

research Melanin Pigmentary Disorders: Treatment Update

84 citations, April 2005 in “Dermatologic Clinics”

Treatments for melanin disorders exist, but more effective options needed.

research Pseudofolliculitis Barbae: Overview and Treatment Modalities

19 citations, May 2007 in “Dermatologic therapy”

The document concludes that various treatments, including laser therapy, are effective for managing pseudofolliculitis barbae, especially in darker skin types.

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