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    Glossary Hyperammonemia

    condition with elevated ammonia levels in the blood

    Hyperammonemia is a condition characterized by elevated levels of ammonia in the blood. Ammonia is a waste product that is typically processed by the liver and converted into urea, which is then excreted in urine. When the liver is unable to effectively process ammonia, due to liver disease or genetic disorders affecting the urea cycle, it can accumulate in the bloodstream and become toxic, potentially leading to neurological symptoms such as confusion, lethargy, and in severe cases, coma.

    Research 10 of 49

    1. Hyperammonemic encephalopathy without hepatic dysfunction due to treatment with valproate: four cases and a mini review Psychiatry and Clinical Psychopharmacology · 2018 · 7 citations
    2. Hyperammonemia with Valproic Acid: Colonic Ischemia Associated with “Triptan” Use Visual Side Effects with Pegylated Interferon: Alopecia Areata with Infliximab: Adverse Effects Seen with Medications Used for Irritable Bowel Syndrome Hospital pharmacy · 2004 · 2 citations
    3. TREATMENT OF VALPROATE‐INDUCED HYPERAMMONEMIA Journal of the American Geriatrics Society · 2005 · 12 citations
    4. Two Hypomorphic Alleles of Mouse Ass1 as a New Animal Model of Citrullinemia Type I and Other Hyperammonemic Syndromes ˜The œAmerican journal of pathology · 2010 · 35 citations
    5. The prevalence and management of side effects of lithium and anticonvulsants as mood stabilizers in bipolar disorder from a clinical perspective International Clinical Psychopharmacology · 2013 · 65 citations
    6. Serum Biotinidase Activity in Children Treated With Valproic Acid and Carbamazepine Journal of child neurology · 2009 · 16 citations
    7. Diagnosis and treatment of methylmalonic acidemia in 14 cases 2004 · 2 citations
    8. Valproic Acid is an Effective Anti-Emetic Treatment in Alexander Disease (P10-9.010) Neurology · 2023
    9. Hypertensive urgency in a child with focal epilepsy: Is it sodium valproate induced? Indian Journal of Pharmacology · 2022
    10. オルニチン・トランスカルバミラーゼ(OTC)欠損(spf・ash)マウスへのOTC遺伝子導入 1991
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