12 citations
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March 2018 in “Analytical chemistry” This study found that a new analytical approach revealed an increased brain pregnenolone level following finasteride treatment in a mouse model, suggesting potential for improved understanding of neurosteroid roles in brain excitability.
3 citations
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February 2021 in “Molecules” In this study, researchers developed a sensitive assay to measure the inhibition of steroid 5-α reductase (5AR) by chemicals like finasteride and dutasteride, revealing species-specific differences in inhibitor efficacy between human and fish cell lines.
38 citations
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June 2005 in “Matrix Biology” Minoxidil affects collagen-related genes, potentially helping treat fibrosis.
49 citations
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October 2017 in “Nutrients” This study observed that the ethyl acetate extract of Equisetum debile showed high activity against 5α-reductase and lipid peroxidation with no cytotoxicity on dermal papilla cells.
27 citations
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April 2013 in “Reviews in endocrine and metabolic disorders” The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.