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      Cutaneous Manifestations of Mucopolysaccharidoses

      research Cutaneous Manifestations of Mucopolysaccharidoses

      8 citations , September 2016 in “Pediatric dermatology”
      This review discusses the diverse clinical manifestations of mucopolysaccharidoses in children and emphasizes the importance of early diagnosis and treatment initiation, but it reports no new clinical findings.
      Acne as a Chronic Systemic Disease

      research Acne as a chronic systemic disease

      71 citations , November 2013 in “Clinics in Dermatology”
      This review discusses the chronic nature of acne and its association with various systemic diseases, but reports no new clinical findings, highlighting the need for further study on its nutritional or genetic links.

      research High-coverage genome of the Tyrolean Iceman reveals unusually high Anatolian farmer ancestry

      31 citations , August 2023 in “Cell Genomics”
      This study produced a high-coverage genome of the Tyrolean Iceman, revealing no Steppe-related ancestry but significant Anatolian-farmer-related ancestry, and found genetic markers associated with darker skin, male-pattern baldness, type 2 diabetes, and obesity, aligning with observations of his mummified body.
      Cantú Syndrome with Coexisting Familial Pituitary Adenoma

      research Cantú syndrome with coexisting familial pituitary adenoma

      14 citations , January 2018 in “Endocrine”
      This report describes a three-generation family with Cantú syndrome linked to a novel ABCC9 gene variant, featuring acromegaloid appearance and hypertrichosis without growth hormone abnormalities, and suggests a potential association with pituitary adenomas.

    Community Join

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      community Hair loss research is a money grab

       227 upvotes 10 months ago
      Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

      community Petition Alert: Let's Get PP405 Phase 3 Trials in Germany by 2026!

       55 upvotes 1 year ago
      A user is advocating for Phase 3 trials of the hair loss treatment PP405 to be conducted in Germany, citing benefits like a diverse patient base and faster access for European patients. Despite skepticism about the petition's influence, the user believes it can demonstrate significant interest and potentially influence strategic decisions.

      community Sugar and Hair loss connections

      in Research/Science  41 upvotes 1 year ago
      High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.