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This review discusses the use of human and animal-derived placental and umbilical extracts in cosmetics, highlighting insufficient data to establish their safety and recommending they should not have metabolic or endocrine activity.

This review discusses peptide "biogenic stimulants" from human placenta extracts, highlighting their potential wide-ranging clinical applications across multiple diseases, and reports no new clinical results.

This study found that human placenta extract may enhance hair growth by increasing PG-E2 and PG-F2a production while decreasing PG-D2 levels in cultured hair follicle keratinocytes.

This review discusses the potential of human placental extract (HPE) in cartilage regenerative medicine for osteoarthritis, noting its significant anti-inflammatory and regenerative properties observed in vitro and in vivo studies, but reports no new clinical results.

This study found that human placental extract promoted hair growth and influenced cellular pathways in vitro and rat models, suggesting potential for future hair loss treatments.