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Effects of Polygoni Multiflori Radix on Elastase and Collagenase Activities and Procollagen Synthesis in Hs68 Human Fibroblasts

research Effects of Polygoni Multiflori Radix on the Elastase, and Collagenase Activities and the Procollagen Synthesis in Hs68 Human Fibroblasts

2 citations , January 2014 in “The Korea Journal of Herbology”

This study found that Polygoni Multiflori Radix (PMR) reduced collagenase and elastase activity after UVB damage in fibroblasts, suggesting potential anti-aging properties for cosmetic use.

Nonsteroidal Inhibitors of Human Type I Steroid 5α-Reductase

research Nonsteroidal inhibitors of human type I steroid 5-.alpha.-reductase

89 citations , February 1993 in “Journal of Medicinal Chemistry”

This research article focuses on nonsteroidal inhibitors of human type I steroid 5-alpha-reductase but reports no new results.

research Inhibition of TNF-α-Induced Collagen Degradation and Oxidative Damage by Centipeda minima and Brevilin A in Human Dermal Fibroblasts

1 citations , May 2025 in “Current Issues in Molecular Biology”

This study found that Centipeda minima and brevilin A significantly reduced oxidative stress and inflammation in human dermal fibroblasts, suggesting their potential to protect against skin aging and inflammation.

research Effects of Topical application of Astragalus membranaceus in Spontaneous Alopecia Mice Model

4 citations , March 2018 in “Daehan han'yi hag'hoeji/Journal of Korean medicine”

This study found that topical application of Astragalus membranaceus extract induced hair regrowth and reduced immune response markers in mice with natural hair loss.

research LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1.

53 citations , June 1993 in “Proceedings of the National Academy of Sciences of the United States of America”

This study identified LY191704 as a specific noncompetitive inhibitor of human 5 alpha-reductase type 1, which may be useful in treating endocrine disorders related to DHT overproduction.

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community Hair and normal skin created from human pluripotent stem cells for the first time

86 upvotes 6 years ago

Human pluripotent stem cells have been used to create hair and skin, potentially offering a new solution for baldness. A user also mentioned starting finasteride but experiencing unexpected hair thinning.

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