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research BH08 Evaluating quality-of-life measures for alopecia: a comparative analysis of Dermatology Life Quality Index and Hospital Anxiety and Depression Scale correlations with disease severity

June 2024 in “British Journal of Dermatology”

This study reported that while both DLQI and HADS showed moderate correlations, only DLQI correlated with clinician-assessed disease severity in patients with alopecia.

research Alopecia Areata and Its Association With Anxiety and Depression: A Case–Control Study in Patients Referred to Dermatology Clinics

January 2026 in “International Journal of Clinical Practice”

This study found that individuals with alopecia areata have higher levels of anxiety and depression compared to healthy individuals, with longer disease duration linked to increased anxiety and severe severity predicting higher depression.

research Evaluation of Quality of Life, Anxiety and Depression in Patients with Alopecia Areata: A Prospective Case-Control Study

September 2025 in “Cyprus Journal of Medical Sciences”

In this study, patients with acute alopecia areata experienced significantly higher anxiety and depression levels, along with a worsened quality of life, compared to a control group, underscoring the importance for clinicians to address these psychiatric issues early in the condition.

Mental Health in Visible Skin Disorders: Assessing Anxiety and Depression in Vitiligo and Alopecia Areata Patients Compared to Healthy Peers

research Mental Health in Visible Skin Disorders: Assessing Anxiety and Depression in vitiligo and alopecia areata patients compared to Healthy Peers

August 2025 in “Libyan Medical Journal”

This study found that patients with vitiligo or alopecia areata have higher levels of anxiety and depression compared to healthy individuals, though no significant differences were observed between the two patient groups, highlighting the psychological impact of these dermatological conditions.

Improvement in Health-Related Quality of Life and Symptoms of Anxiety and Depression in Patients with Alopecia Areata Randomized to Baricitinib or Placebo: Results from Two International Randomized Controlled Trials

research Improvement in health‐related quality of life and symptoms of anxiety and depression in patients with alopecia areata randomized to baricitinib or placebo: Results from two international randomized controlled trials

November 2023 in “JEADV Clinical Practice”

In this study, adults with severe alopecia areata experienced greater improvements in hair regrowth, health-related quality of life, and reduced anxiety and depression symptoms after 36 weeks of treatment with baricitinib compared to placebo.

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community Recovered from dark finasteride side effects

4 upvotes 4 years ago

The user experienced severe side effects from finasteride, including depression and anxiety, but recovered with DHT injections, sleep medication, and Ayurvedic treatments. They now maintain hair health with minoxidil, PRP therapy, and a good diet, advising against self-diagnosis and recommending consulting a doctor.

community How finasteride lowers brain's happiness steroid allopregnanolone and causes depression: systemic dihydroprogesterone crosses blood brain barrier, you don't even need finasteride and brain 5ar for that

288 upvotes 1 year ago

Finasteride may lower allopregnanolone levels, potentially affecting mood, but many users report improved mental health due to reduced hair loss. Experiences with finasteride and dutasteride vary, with some experiencing side effects and others finding them beneficial for hair retention and overall happiness.

community I am putting my hair loss treatment on hold until my mental health is better.

in Update 21 upvotes 2 years ago

OP is pausing hair loss treatments to focus on mental health due to anxiety and side effects from RU58841. They plan to try topical finasteride and minoxidil after recovering from pneumonia.

community Finasteride - impact on Neurosteroids, which yes, \are important and not a garbage hormone

in Research/Science 163 upvotes 1 year ago

Finasteride may affect neurosteroids, impacting mood and sexual function, with varied user experiences. Some report side effects like depression and sexual dysfunction, while others find it effective for hair retention or prefer alternatives like Dutasteride or topical treatments.

community On Dutasteride 0.5mg ED for almost 2 years. Increasingly shedding hair for more than 5 months.

in Finasteride/Dutasteride 7 upvotes 1 year ago

The user experienced increased hair shedding after switching from finasteride to dutasteride, despite lifestyle improvements and additional treatments like oral minoxidil and PRP. They are concerned about persistent shedding, changes in hormone levels, and potential chronic telogen effluvium, and are considering a scalp biopsy for further investigation.

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SMP Specialist
Sandro Salerno
Zürich, Switzerland

Sandro Salerno