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Did you mean Thyroid Hormone Replacement Therapy?

Glossary Thyroid Hormone Replacement Therapy

supplements thyroid hormones for underactive or removed thyroid glands

Thyroid Hormone Replacement Therapy (THRT) is a medical treatment used to supplement or replace the thyroid hormones in individuals whose thyroid gland is underactive (hypothyroidism) or has been removed. This therapy typically involves the daily administration of synthetic thyroid hormones, such as levothyroxine, to help regulate the body's metabolism, energy levels, and overall hormonal balance.

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Research

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research MON-203 Dermatological Effects Of Hormone Replacement Therapy

October 2025 in “Journal of the Endocrine Society”

This research review observed that topical hormone replacement therapy, particularly estradiol and estradiol-testosterone combinations, significantly increased Type I and III collagen synthesis in the skin of postmenopausal women, suggesting benefits against collagen loss-related skin aging effects such as reduced elasticity and increased dryness.

research Hormone replacement therapy and the skin

138 citations , May 2000 in “Maturitas”

This review discusses the effects of estrogen on skin and reports no new clinical results; it highlights estrogen's potential benefits on skin thickness, collagen quality, and hair follicle life cycle.

research Skin climacteric aging and hormone replacement therapy

27 citations , March 2006 in “Journal of cosmetic dermatology”

This review examines the effects of menopause on skin aging and suggests hormone replacement therapy may improve some symptoms, without providing new clinical findings.

research The role of androgens in hormone replacement therapy

6 citations , September 2005 in “Expert Opinion on Pharmacotherapy”

This review discusses the role of androgens in women's sexual health and highlights the need for further research on androgen replacement therapy to optimize quality of life, but reports no new clinical results.

research Managing Menopausal Skin Changes: A Narrative Review of Skin Quality Changes, Their Aesthetic Impact, and the Actual Role of Hormone Replacement Therapy in Improvement

4 citations , August 2025 in “Journal of Cosmetic Dermatology”

This study found that while hormone replacement therapy can improve skin aging in menopausal women, inconsistent findings and a lack of robust clinical trials mean it isn't recommended purely for skin benefits.

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Community Join

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community Taking HRT medication not only cured my thinning hair, it gave me better hair than I ever had before

in Transgender 12 upvotes 9 months ago

Hormone replacement therapy with spironolactone and estradiol significantly improved hair thickness and growth, surpassing previous treatments like dutasteride, finasteride, and minoxidil. The user experienced regrowth in receded areas and a more youthful appearance.

community FTM/NB Hairloss from HRT, treatment started and feeling hopeless.

in Transgender 61 upvotes 1 year ago

A non-binary individual experienced hair loss after stopping hormone replacement therapy and is using oral Dutasteride, oral Minoxidil, and ketoconazole shampoo. They are hopeful for regrowth but may use wigs due to the high cost and uncertain effectiveness of additional treatments like mesotherapy and PRP.

community HRT temple regrowth - 0 months, 3 months, 6 months

22 upvotes 2 months ago

The conversation is about hair regrowth progress using hormone replacement therapy (HRT) with Estradiol and Cyproterone, without using Minoxidil. The user shares progress pictures over 0, 3, and 6 months.

community 19 months Topical Min/Fin - 7 months HRT

1072 upvotes 3 months ago

The user experienced significant hair regrowth and fullness after starting hormone replacement therapy (HRT) with sublingual estrogen and spironolactone, in addition to using a topical solution of minoxidil, finasteride, ketoconazole, and biotin. They noted initial shedding phases but emphasized that shedding is a sign of future growth.

community (MTF 35) Results of 18 Months of HRT

775 upvotes 8 months ago

A transgender woman experienced significant hair regrowth after 18 months of hormone replacement therapy (HRT) with estrogen and bicalutamide. The discussion notes HRT's effectiveness for hair regrowth but warns against its use for cisgender men due to feminizing effects.

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