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research Phytochemicals as Modulators of Human Endocrine Function: Bridging Traditional Remedies and Hormonal Health

December 2025

This chapter explores the potential of phytochemicals in modulating human endocrine function, emphasizing the growing interest in plant-derived alternatives to synthetic medications for managing metabolic and hormonal disorders often linked to chemical exposures and lifestyle factors.

research Berberine as a Modulator of Metabolic and Hormonal Dysregulation in PCOS: Mechanisms of Action and Clinical Implications - A Narrative Review

May 2026 in “Quality in Sport”

This study suggests that berberine may offer multiple benefits for women with polycystic ovary syndrome by improving metabolic and hormonal profiles, though further research is needed on its long-term effects on reproductive outcomes.

research Epidemiology and Management of Acne in Adult Women

5 citations , January 2014 in “Current Dermatology Reports”

This review discusses various treatments for adult acne in women, including topical, systemic, and alternative therapies, and reports no new clinical results.

research Nanotechnology-Driven Antioxidants and Immunomodulators for Polycystic Ovary Syndrome (PCOS) Therapy

July 2025

This chapter reveals how nano-antioxidants and immune-modulatory agents could offer innovative treatment strategies for PCOS by addressing the inflammation and immune system dysregulation often overlooked in traditional hormonal treatments.

research DERMATOLOGICAL MANIFESTATIONS OF POLYCYSTIC OVARY SYNDROME

February 2024 in “Brazilian Journal of Implantology and Health Sciences”

This review discusses the high prevalence of dermatological manifestations like hirsutism and acne in PCOS patients and explores various therapeutic approaches, highlighting the need for early recognition and treatment.

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Community Join

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community Dht is a real bastard of a hormone it’s annoying to get rid of it

335 upvotes 5 days ago

DHT affects hair loss and hormonal balance, with treatments like finasteride, dutasteride, and minoxidil being discussed. Users share experiences with side effects, gym performance, and the impact on libido, with some suggesting complex treatment regimens.

community DHT results after 1 year on dutasteride, confused and seeking guidance

in Finasteride/Dutasteride 107 upvotes 1 year ago

The user is experiencing rapid hair loss despite using dutasteride, finasteride, and minoxidil, and is concerned about high estradiol and testosterone levels. They are advised to consult an endocrinologist for potential hormonal imbalances.

community My as soon as my son turns 18:

1983 upvotes 6 months ago

Hair loss treatments like finasteride, dutasteride, and minoxidil are discussed, with differing views on when to begin treatment. Some suggest early use, while others warn of hormonal side effects from starting too young.

community Does RU58841 potentially cause cancer?

in Research/Science 1 year ago

RU58841 may pose cancer risks due to its antiandrogen properties and lack of long-term safety data. Using it is considered a high-risk experiment with unknown potential for harm.

community Do you believe these studies are real or just fear mongering

in Finasteride/Dutasteride 157 upvotes 11 months ago

Finasteride can regrow hair but may cause depression and suicidal thoughts in some users. The connection between finasteride and mental health issues is debated, with some attributing it to pre-existing conditions or stress.

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Learn

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learn microbiota modulator

learn Lavender

Is lavender effective for hormonal hair loss or just stress? No study has tested lavender for stress-related or hormonal hair loss in people; the hair-growth evidence is one mouse study. Case reports link lavender products to breast growth in children, so keep them away from children.

learn Bicalutamide

Why do some women use bicalutamide for hormonal hair loss? Some dermatologists prescribe bicalutamide off-label for female pattern hair loss, although its US label says it should not be used in women; the one randomised trial found no added benefit over oral minoxidil. The label warns of severe and fatal liver injury, requiring liver blood tests, and the drug must not be used in pregnancy.

learn Estradiol

Can Estradiol cause side effects in people without a hormonal imbalance? Estradiol can cause side effects even in hormonally balanced individuals.

learn Vitamin B6

Is Vitamin B6 helpful for stress-related or hormonal hair loss? Vitamin B6 may support overall health but lacks strong evidence for preventing hair loss.

learn Adenosine

Adenosine : Can it help if my hair loss is due to a hormonal imbalance like PCOS or DHT? Adenosine does not act on hormones, and it has not been studied in PCOS. Small trials in pattern hair loss showed thicker hairs.

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