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research Assessment of the impact of VDR polymorphisms on selected hormonal, metabolic and mineral balance markers in young women with hyperandrogenism

January 2025 in “Ginekologia Polska”

In this study, researchers found that certain vitamin D receptor gene polymorphisms are significantly related to insulin concentration during a glucose tolerance test in young women with hyperandrogenism, but these polymorphisms did not affect bone metabolism or other biochemical parameters.

research Chromium supplementation does not improve weight loss or metabolic and hormonal variables in patients with polycystic ovary syndrome: A systematic review

11 citations , April 2018 in “Nutrition Research”

This review found that chromium supplementation has limited effects on weight reduction, glucose control, lipid profile, and hormonal balance in women with PCOS, highlighting the need for further research.

research Androgenic alopecia in men: the significance of genetic, hormonal and metabolic factors (prospective cohort comparative study)

December 2022 in “Rossiiskii Zhurnal Kozhnykh i Venericheskikh Boleznei”

In this study, researchers found that genetic and non-genetic factors, including deficiencies in micronutrients like zinc and vitamins, play varying roles in the development of androgenetic alopecia in men.

research Berberine as a Modulator of Metabolic and Hormonal Dysregulation in PCOS: Mechanisms of Action and Clinical Implications - A Narrative Review

May 2026 in “Quality in Sport”

This study suggests that berberine may offer multiple benefits for women with polycystic ovary syndrome by improving metabolic and hormonal profiles, though further research is needed on its long-term effects on reproductive outcomes.

research Metabolic and hormonal changes during the molt of captive gray seals (Halichoerus grypus)

51 citations , May 1996 in “American journal of physiology. Regulatory, integrative and comparative physiology/American journal of physiology. Regulatory, integrative, and comparative physiology”

In this study, captive gray seals exhibited increased resting metabolic rates and elevated thyroid hormone levels during the final stage of molting, with more pronounced changes in juveniles.

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community How likely do you think it is for PP405 to come out?

in Research/Science 21 upvotes 11 months ago

PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

2 upvotes 1 year ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

in Research 413 upvotes 1 year ago

Treating androgenic alopecia with minoxidil, finasteride, and antiandrogens, alongside exercise, cryotherapy, and natural substances to stimulate cold receptors for better hair growth. The method focuses on enhancing treatment effectiveness by considering environmental and behavioral factors and the role of cold receptors and muscle stress.

community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

in Treatments 451 upvotes 2 years ago

Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

community How do you keep your bloodsugar low on finasteride?

12 upvotes 2 years ago

Finasteride may affect blood sugar and metabolism, with some users reporting increased blood sugar and changes in body composition. To manage potential side effects, users suggest exercise, intermittent fasting, and dietary adjustments.

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Learn

6 / 6 results

learn Neem Oil

Oil from the neem tree, used in traditional remedies

learn Lavender

Is lavender effective for hormonal hair loss or just stress? No study has tested lavender for stress-related or hormonal hair loss in people; the hair-growth evidence is one mouse study. Case reports link lavender products to breast growth in children, so keep them away from children.

learn Bicalutamide

Why do some women use bicalutamide for hormonal hair loss? Some dermatologists prescribe bicalutamide off-label for female pattern hair loss, although its US label says it should not be used in women; the one randomised trial found no added benefit over oral minoxidil. The label warns of severe and fatal liver injury, requiring liver blood tests, and the drug must not be used in pregnancy.

learn Estradiol

Can Estradiol cause side effects in people without a hormonal imbalance? Estradiol can cause side effects even in hormonally balanced individuals.

learn Vitamin B6

Is Vitamin B6 helpful for stress-related or hormonal hair loss? Vitamin B6 may support overall health but lacks strong evidence for preventing hair loss.

learn Adenosine

Adenosine : Can it help if my hair loss is due to a hormonal imbalance like PCOS or DHT? Adenosine does not act on hormones, and it has not been studied in PCOS. Small trials in pattern hair loss showed thicker hairs.

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