learn Pyrilutamide
highly targeted anti-androgen that might have minimal systemic effects
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learn Finasteride
Frontline, gold standard treatment for combatting androgenic alopecia
learn Alfatradiol
a synthetic estrogen used topically as an anti-androgen
learn HMI-115
much-hyped research compound targeting prolactin receptor in scalp
Research
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research Hormonal Evaluation of Hyperandrogenism in Women
The woman's high testosterone levels indicated PCOS, leading to treatment that improved her symptoms.
research Clinical and Hormonal Evaluation of Androgen Excess
Most cases of high male hormone levels in women are due to polycystic ovary syndrome.
research A Clinico-Etiological Evaluation of Hirsutism Patients: A Case Series
The conclusion is that hirsutism is strongly linked to PCOS and higher levels of certain hormones, but not to DHEAS, prolactin, cortisol, or TSH.
research Hormonal Therapy in Dermatology
Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.
research Prevalence of Hormonal and Endocrine Dysfunction in Patients with Lichen Planopilaris: A Retrospective Data Analysis of 168 Patients
Lichen planopilaris (LPP) is linked to androgen excess, while frontal fibrosing alopecia (FFA) is linked to androgen deficiency.
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5 / 518 resultscommunity C’est terrible - at my wits end
A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.
community What treatment should I take? and is it really bad?
OP is experiencing significant hair loss despite GFC and PRP treatments and has abnormal lab results. They are advised to consult a hair-focused dermatologist for further evaluation.
community Just popped my first fin, excited as hell!
A user shared their excitement about starting finasteride for hair loss after trying various ineffective methods. Other users discussed their experiences with finasteride, including shedding phases and side effects, with one mentioning using topical finasteride and minoxidil.
community Diffuse hair loss and scalp biopsies
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community 10 months on fin and hairline destroyed.
A user experienced severe hair shedding and hairline recession after 10 months on finasteride. They are considering switching to dutasteride or adding minoxidil.