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      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects
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      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

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      community 15yo with severe anxiety from Norwood 2.5 and thinning

      in Finasteride/Dutasteride  15 upvotes 2 weeks ago
      A 15-year-old experiencing hair loss and anxiety is using minoxidil and microneedling but is advised against starting finasteride or dutasteride due to age. The discussion emphasizes consulting a doctor, considering hormonal evaluations, and exploring non-medication coping strategies.

      community C’est terrible - at my wits end

      in Female  442 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.
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      community Just popped my first fin, excited as hell!

      in Finasteride/Dutasteride  154 upvotes 7 months ago
      A user shared their excitement about starting finasteride for hair loss after trying various ineffective methods. Other users discussed their experiences with finasteride, including shedding phases and side effects, with one mentioning using topical finasteride and minoxidil.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  828 upvotes 5 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.