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Human FOXN1 Deficiency Is Associated with Alpha Beta Double-Negative and FoxP3 Positive T-Cell Expansions That Are Distinctly Modulated upon Thymic Transplantation

research Human FOXN1 Deficiency Is Associated with Alpha Beta Double-Negative and FoxP3 Positive T-Cell Expansions That Are Distinctly Modulated upon Thymic Transplantation

32 citations , May 2012 in “PloS one”

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

research FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program

69 citations , January 2013 in “Frontiers in Immunology”

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

research FOXN1 Deficient Nude Severe Combined Immunodeficiency

32 citations , January 2017 in “Orphanet journal of rare diseases”

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

research Transplantation Immunology: Solid Organ and Bone Marrow

139 citations , February 2010 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

Transplant success has improved with better immunosuppressive drugs and donor matching.

research First Use of Thymus Transplantation Therapy for FOXN1 Deficiency (Nude/SCID): A Report of 2 Cases

103 citations , January 2011 in “Blood”

Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.

View more "hla-mismatched thymic transplantation" in research →

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community Dermastamping — do you use hyaluronic acid as lubricant?

in Microneedling 3 upvotes 1 year ago

The conversation discusses using high molecular weight hyaluronic acid after microneedling to form a protective barrier, though it's considered expensive and offers marginal improvement. Users share experiences with different microneedling tools like derma rollers, dermastamps, and Dr. Pen, with some opting not to use any products on the scalp.