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research A Novel Epithelial Keratin, hK6irs1, Is Expressed Differentially in All Layers of the Inner Root Sheath, Including Specialized Huxley Cells of the Human Hair Follicle

86 citations, May 2002 in “Journal of Investigative Dermatology”

A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.

research HKAP1.6 And HKAP1.7, Two Novel Human High Sulfur Keratin-Associated Proteins Are Expressed In The Hair Follicle Cortex

24 citations, February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

Two new proteins, hKAP1.6 and hKAP1.7, are found in the hair follicle cortex.

research Characterization of Human Keratin-Associated Protein 1 Family Members

17 citations, June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”

Mutations in hKAP1 genes may cause hereditary hair disorders.

Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-Associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21

research Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-Associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21

98 citations, June 2001 in “Journal of biological chemistry/The Journal of biological chemistry”

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

research Hinokitiol, a Natural Tropolone Derivative, Inhibits TNF-Alpha Production in LPS-Activated Macrophages via Suppression of NF-Kappa B

54 citations, June 2008 in “Planta Medica”

Hinokitiol may help treat hair loss by reducing inflammation and promoting hair growth.

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Community Join

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community KX-826 Phase 3 Failed. Sorry guys...

in Research/Science 48 upvotes 1 year ago

The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

community Pyrilutamide cleared for phase 3 clinical trial in china

in Research/Science 27 upvotes 3 years ago

Hair loss discussion includes Minoxidil, Finasteride, and RU58841 treatments. Pyrilutamide cleared for phase 3 clinical trial in China.

community Pyrilutamide phase III clinical trial results released

in Research/Science 31 upvotes 1 year ago

Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.

community KX-826: Long-Term Safety Results are out!

in Research/Science 155 upvotes 2 months ago

KX-826 initially improves hair growth but declines after 24 weeks, with mild itching as a side effect. Combining it with minoxidil and finasteride may improve results, but long-term effectiveness is uncertain.

community FUT hair transplant in Korea (Before/1 year post op)

in Progress Pictures 88 upvotes 7 months ago

A user shared progress pictures of their FUT hair transplant in Korea, showing results one year post-op. The conversation highlights the density of the hair, the quality of Korean hair treatments, and mentions treatments like Minoxidil, finasteride, and Dutasteride.

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