research Application of histamine receptors H2R, H3R and H4R, but not H1R, in dermatology
This review explores the roles of histamine receptors H2R, H3R, and H4R in treating various dermatoses but reports no new clinical outcomes.
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5 / 1000+ results research FPRL1 Receptor Agonist Peptides Prevent Etoposide-Induced Alopecia in Neonatal Rats
Certain peptides can prevent hair loss in young rats caused by a cancer drug.
research Extracellular Signal-Regulated Kinase Mediates Ebastine-Induced Human Follicle Dermal Papilla Cell Proliferation
In this study, ebastine significantly increased the proliferation of human follicle dermal papilla cells and may contribute to hair regrowth by activating the ERK signaling pathway.
research Advances in histamine-mediated allergy management: Expanding perspectives on cetirizine’s therapeutic, safety, and toxicological implications
This commentary highlights that cetirizine, a widely-used antihistamine, remains effective for various emerging allergic conditions, and new formulations and combination therapies may enhance its effectiveness while being generally well-tolerated.
research Evolution, mechanism of action, and clinical applications of three generations of antihistamines
This review outlines the development and clinical use of three generations of antihistamines, noting that while first-generation drugs have multiple side effects including sedation, second- and third-generation antihistamines offer greater efficacy and safety due to their selective action on peripheral H1 receptors.
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