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The Interaction Between Finasteride and Corticosterone Levels: Implications for Depression and Anxiety-Like Behavior and Hippocampal Synaptic Plasticity in Male Rats

research The Interaction Between Finasteride and Corticosterone Levels: Implications for Depression and Anxiety-Like Behavior and Hippocampal Synaptic Plasticity in Male Rats

May 2025 in “Psychopharmacology”

Chronic finasteride use in male rats doesn't strongly cause depression or anxiety due to adaptive stress hormone changes.

research Locally Synthesized 17-Beta-Estradiol Reverses Amyloid-Beta-42-Induced Hippocampal Long-Term Potentiation Deficits

January 2024 in “International journal of molecular sciences”

A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.

research Ethanol Enhances Neurosteroidogenesis in Hippocampal Pyramidal Neurons by Paradoxical NMDA Receptor Activation

82 citations , July 2011 in “Journal of Neuroscience”

Ethanol boosts brain steroid production by activating NMDA receptors, affecting memory formation.

Midazolam Inhibits Hippocampal Long-Term Potentiation and Learning Through Dual Central and Peripheral Benzodiazepine Receptor Activation and Neurosteroidogenesis

research Midazolam Inhibits Hippocampal Long-Term Potentiation and Learning Through Dual Central and Peripheral Benzodiazepine Receptor Activation and Neurosteroidogenesis

97 citations , December 2010 in “Journal of Neuroscience”

Midazolam impairs learning and memory by increasing neurosteroids through specific receptor activation.

research Corticosterone Enhances the Potency of Ethanol Against Hippocampal Long-Term Potentiation via Local Neurosteroid Synthesis

11 citations , July 2015 in “Frontiers in Cellular Neuroscience”

Corticosterone makes ethanol more effective at blocking brain processes important for learning and memory.

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community Finasteride and “anti-aging” effects

in Treatment 218 upvotes 6 months ago

Finasteride may help users look younger by suppressing DHT, affecting skin and hair. Users also emphasize skincare, sunscreen, and lifestyle for maintaining a youthful appearance.

community Quick rant about fin/dut posts on this sub.

in Finasteride/Dutasteride 175 upvotes 5 years ago

Hair loss treatments Finasteride and Dutasteride are discussed, with emphasis on their safety and effectiveness. Users share frustration about fear-mongering and side effect discussions, suggesting trust in scientific studies and FDA approval.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 2 years ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

MagicBold in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Finasteride does deplete important nuero-active steroids

in Research/Science 9 upvotes 2 years ago

Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

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