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      research Podophyllotoxin-loaded solid lipid nanoparticles for epidermal targeting

      297 citations , December 2005 in “Journal of controlled release”
      This study found that POD-loaded solid lipid nanoparticles using 0.5% poloxamer 188 and 1.5% soybean lecithin (P-SLN) improved epidermal targeting and POD accumulation in porcine skin compared to traditional tincture.
      Application of Nanoemulsions in Cosmetics

      research Application of Nanoemulsions in Cosmetics

      23 citations , January 2018 in “Elsevier eBooks”
      This chapter reviews formulation principles for creating cosmetic nanoemulsions and applications targeting skin and hair care, but does not present new experimental results.
      Keratin-Based Particles for Protection and Restoration of Hair Properties

      research Keratin‐based particles for protection and restoration of hair properties

      17 citations , July 2018 in “International Journal of Cosmetic Science”
      This study found that keratin-based particles were able to recover and enhance the mechanical properties and thermal stability of virgin and overbleached Asian hair, improving its strength and smoothness by around 40%, and demonstrated safety in human skin keratinocytes.

      research Gelatin nanoparticles & nanocrystals for dermal delivery

      2 citations , January 2014
      This study reported that ultrafine gelatin nanoparticles produced by a modified desolvation technique offer advantages for dermal drug delivery, including smaller particle size, higher drug loading, and faster release compared to traditional gelatin nanoparticles.
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      community Extreme caution: my experience using Ru58841 only once

      in Treatment  10 upvotes 1 year ago
      An 18-year-old experienced severe side effects, including heart palpitations and high blood pressure, after using RU58841 once, leading to a referral to cardiology for suspected left ventricular hypertrophy. The user regrets using RU58841 and seeks advice on recovery, while others suggest preexisting conditions or genetic predispositions may be factors.

      community Ive been on Finasteride only 1,5 years

       85 upvotes 1 month ago
      The user has been taking 1mg finasteride daily for 1.5 years with significant hair regrowth and no major side effects, but is considering a hair transplant for thinning areas. They have avoided minoxidil due to concerns about high blood pressure and body hair growth.

      community New 2025 study: high dose oral minoxidil (up to 10mg)

      in Research/Science  80 upvotes 11 months ago
      High-dose oral minoxidil (>5 mg/day) can increase hair density in some men with androgenetic alopecia, but side effects like extra body hair and heart issues are common. Gradual dose increase is advised, but adverse effects may lead to discontinuation or dose adjustments.

      community Control your blood pressure - for me this was my root issue

       9 upvotes 1 year ago
      Managing blood pressure can help with hair loss, as seen with the use of medications like Cialis and oral minoxidil, which improved hairline and blood pressure. Lifestyle changes, such as reducing stimulant use and adjusting testosterone replacement therapy (TRT) doses, also play a role in addressing hair loss and overall health.
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